Triacsin C
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- Application
- Inhibition (Inh)
- Purpose
- Acyl-CoA synthetase inhibitor
- Characteristics
- Fatty acyl-CoA synthase inhibitor.
- Purity
- 90 % (HPLC), NMR (Conforms).
- Chemical Name
- (3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane
- Formula
- C11H17N3O
- Solubility
- Soluble in DMSO (25 mg/ml) or methanol (5 mg/ml)
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- Comment
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Source: Synthetic.
Appearance: Oil dissolved in DMSO (1mg/ml) - Restrictions
- For Research Use only
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- Format
- Oil
- Precaution of Use
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- Handling Advice
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- Storage
- -20 °C
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- Background
- Triacsin C is a potent inhibitor of long fatty acyl CoA synthetase. It blocks beta-cell apoptosis. It also blocks the de novo synthesis of triglyercides, diglycerides and cholesterol esters, interfering with lipid metabolism. It is also a potent vasodilator.
- Molecular Weight
- 207.27
- CAS-No
- 76896-80-5
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