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Triacsin C

Inh 76896-80-5 (3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane
Catalog No. ABIN1027762
  • Application
    Inhibition (Inh)
    Purpose
    Acyl-CoA synthetase inhibitor
    Characteristics
    Fatty acyl-CoA synthase inhibitor.
    Purity
    90 % (HPLC), NMR (Conforms).
    Chemical Name
    (3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane
    Formula
    C11H17N3O
    Solubility
    Soluble in DMSO (25 mg/ml) or methanol (5 mg/ml)
  • Comment

    Source: Synthetic.
    Appearance: Oil dissolved in DMSO (1mg/ml)

    Restrictions
    For Research Use only
  • Format
    Oil
    Precaution of Use
    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
    Handling Advice
    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
    Storage
    -20 °C
  • Background
    Triacsin C is a potent inhibitor of long fatty acyl CoA synthetase. It blocks beta-cell apoptosis. It also blocks the de novo synthesis of triglyercides, diglycerides and cholesterol esters, interfering with lipid metabolism. It is also a potent vasodilator.
    Molecular Weight
    207.27
    CAS-No
    76896-80-5
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