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CI-994

Inh 112522-64-2 4-(Acetylamino)-N-(2-aminophenyl)benzamide
Catalog No. ABIN7233242
  • Application
    Inhibition (Inh)
    Purpose
    HDAC inhibitor
    Characteristics
    Orally active histone deacetylase (HDAC) inhibitor, IC50 = 0.9, 0.9, 1.2 and >20 μM for HDAC1, HDAC2, HDAC3 and HDAC8 respectively. Mediates G1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo. Increases neuroplasticity during memory extinction. Protects beta cells from cytokine-induced apoptosis.
    Purity
    >98 %
    Chemical Name
    4-(Acetylamino)-N-(2-aminophenyl)benzamide
    Formula
    C15H15N3O2
    Solubility
    Soluble in DMSO (up to 25 mg/ml)
  • Restrictions
    For Research Use only
  • Format
    Powder
    Storage
    -20 °C
  • Background
    PD-123654, N-acetyl-dinaline, GOE-5549,Cytokine,Epigenetics,Apoptosis inducer,Proliferation,Posttranslational modification,Protein deacetylase,Neuroscience,Cell death,Inflammation,Diabetes,Cell cycle,Chromatin
    Molecular Weight
    269.30
    CAS-No
    112522-64-2
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