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Fluorouracil (5-Fluoracil, 5-FU)

InhA, Func 51-21-8
Catalog No. ABIN3219697
  • Application
    Inhibition Assay (InhA), Functional Studies (Func)
    Purpose
    A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
    Characteristics
    Tradename: CARAC
    Source of Compound: synthetic, Ro-2-9757
    Target: HIV Integrase,DNA/RNA Synthesis inhibitor
    Receptor: HIV Integrase,RNA synthesis
    Purification
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Purity
    99 % +
    Formula
    C4H3FN2O2
    Solubility
    Very soluble in water
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Solid
    Storage
    -20 °C
    Storage Comment
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Expiry Date
    24 months
  • Background
    DNA Damage/DNA Repair,Microbiology & Virology,Proteases/Proteasome
    Molecular Weight
    130.08 g/mol
    CAS-No
    51-21-8
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