ITM2C Proteins

(Integral Membrane Protein 2C (ITM2C))

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C- terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).

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ITM2C Protein (AA 1-267) (His tag)

custom-made ITM2C Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant ITM2C Protein, UniprotID Q9NQX7

3 images

Catalog No. ABIN7548560

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Datasheet

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Datasheet as PDF

ITM2C Protein (AA 1-269) (His tag)

custom-made ITM2C Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Itm2c Protein, UniprotID Q91VK4

3 images

Catalog No. ABIN7559993

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Datasheet

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Datasheet as PDF

ITM2C Protein (AA 1-269) (Strep Tag)

custom-made ITM2C Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3127295

Details

Datasheet

Details

Datasheet as PDF

ITM2C Protein (AA 1-267) (Strep Tag)

custom-made ITM2C Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3118420