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anti-Human AGT Antibodies:
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Human Polyclonal AGT Primary Antibody for ELISA, IHC - ABIN1583980
Mateos, Ismail, Gil-Bea, Leoni, Winblad, Björkhem, Cedazo-Mínguez: Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease. in Journal of Alzheimer's disease : JAD 2011
Show all 11 Pubmed References
Human Polyclonal AGT Primary Antibody for ICC, IF - ABIN447446
Dimitrijevic, Rissler, Luts, Edvinsson: Reduced expression of angiotensin II and angiotensin receptor type 1 and type 2 in resistance arteries from nasal lesions in granulomatosis with polyangiitis (Wegener's granulomatosis). in Scandinavian journal of rheumatology 2011
Show all 6 Pubmed References
Human Monoclonal AGT Primary Antibody for WB - ABIN1882204
Desong Liu, Fang Lu, Songhui Zhai, Liu Wei, Shi Ma, Xiuying Chen, Liqun Dong, Yannan Guo, Jin Wu, Zheng Wang: Renin-angiotensin system gene polymorphisms in children with Henoch-Schönlein purpura in West China. in Journal of the renin-angiotensin-aldosterone system : JRAAS 2010
Show all 3 Pubmed References
Human Monoclonal AGT Primary Antibody for WB - ABIN1882205
Kieć-Wilk, Olszanecka, Mikołajczyk, Kawecka-Jaszcz et al.: [Role of the M235T (c.704c>T) polymorphism of angiotensynogen gene as well as A724A (c.2171G>A) polymorphism of SERCA2a gene in ethiopathogenesis of left ventricular hypertrophy in essential... in Przegla̧d lekarski 2010
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Human Monoclonal AGT Primary Antibody for ELISA, WB - ABIN559812
Jain, Li, Patil, Kumar: HNF-1alpha plays an important role in IL-6-induced expression of the human angiotensinogen gene. in American journal of physiology. Cell physiology 2007
Show all 2 Pubmed References
Human Monoclonal AGT Primary Antibody for ELISA, WB - ABIN968948
Xu, Carretero, Lin, Cavasin, Shesely, Yang, Reudelhuber, Yang: Role of cardiac overexpression of ANG II in the regulation of cardiac function and remodeling postmyocardial infarction. in American journal of physiology. Heart and circulatory physiology 2007
Show all 2 Pubmed References
Human Polyclonal AGT Primary Antibody for IHC, IHC (p) - ABIN4352882
Bachmann, Burté, Pramana, Conte, Brown, Orimadegun, Ajetunmobi, Afolabi, Akinkunmi, Omokhodion, Akinbami, Shokunbi, Kampf, Pawitan, Uhlén, Sodeinde, Schwenk, Wahlgren, Fernandez-Reyes, Nilsson: Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria. in PLoS pathogens 2014
Angiotensin II initiates hepatocyte epithelial-mesenchymal transition by activating the NOX-derived H2O2-mediated NLRP3 (show NLRP3 Antibodies) inflammasome/IL-1ss/Smad (show SMAD1 Antibodies) circuit.
present study has demonstrated, for the first time, that high glucose augments AGT (show AGXT Antibodies) in human RPTCs through HNF-5, which provides a potential therapeutic target for diabetic nephropathy
AngII-dependent phosphorylation of LCP1 (show LCP1 Antibodies) in cultured podocytes was mediated by the kinases ERK (show EPHB2 Antibodies), p90 (show CANX Antibodies) ribosomal S6 kinase (show RPS6KB1 Antibodies), PKA, or PKC (show PRRT2 Antibodies). LCP1 (show LCP1 Antibodies) phosphorylation increased filopodia formation.
Autosomal dominant polycystic kidney disease (ADPKD), uniquely increases urinary angiotensinogen and renin (show REN Antibodies) excretion despite their circulating levels being comparable with those in non-ADPKD chronic kidney disease.
Quaternary interactions and supercoiling modulate the cooperative DNA binding of AGT (show AGXT Antibodies).
results show that SNPs in the Hap (show SAFB Antibodies)-I of the hAGT gene promote high-fat diet-induced binding of transcription factors GR, CEBP-beta (show CEBPB Antibodies) and STAT3 (show STAT3 Antibodies), which lead to elevated expression of the hAGT gene in hepatic and adipose tissues
Angiotensinogen import and subsequent trafficking to the mitochondria occurs in proximal kidney tubules.
Transgenic mice expressing human AGT (show AGXT Antibodies) in the subfornical organ AGT (show AGXT Antibodies) and possibly ANG I/ANG II into the cerebral ventricles.
AngII could induce pulmonary injury by triggering endothelial barrier injury, and such process may be related to the dephosphorylation of Y685-VE-cadherin (show CDH5 Antibodies) and the endothelial skeletal rearrangement
Renin-angiotensin system transgenic mouse model suggests that renal injury in preeclampsia may be mediated through local VEGF.
adipocyte-derived Agt (show AGXT Antibodies) has essentially no contribution to the plasma concentration and no impact on blood pressure compared to liver-derived Agt (show AGXT Antibodies).
Lung ischemia-reperfusion injury causes a dysregulation of circulating Ang 2 (show ANGPT2 Antibodies) levels and plasma PREP (show PREP Antibodies) activity, although no direct link between both phenomena could be shown.
Inhibition of TLR4 (show TLR4 Antibodies) ameliorates AngII-impaired cavernosal relaxation, decreases TNF-alpha (show TNF Antibodies) levels, and restores Nitric Oxide bioavailability, demonstrating that TLR4 (show TLR4 Antibodies) partly mediates AngII-induced cavernosal dysfunction.
Our study is the first to show the important role of IL-6 (show IL6 Antibodies) in regulating cardiac pathogenesis via inflammation and apoptosis during AngII-induced hypertension. We also provide a novel link between IL-6 (show IL6 Antibodies)/STAT3 (show STAT3 Antibodies) and EndoG (show ENDOG Antibodies)/MEF2A (show MEF2A Antibodies) pathway that affects cardiac hypertrophy during AngII stimulation.
this study demonstrated that Ang II could increase TRPC6 (show TRPC6 Antibodies) induced Ca(2 (show CA2 Antibodies)+) influx and enhance autophagy through increasing reactive oxygen species levels in podocytes, and autophagy could protect Ang II-treated podocytes.
Snell, GHKRO, and PAPPA (show PAPPA Antibodies)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT (show MGMT Antibodies)) and N-myc downstream-regulated gene 1 (NDRG1 (show NDRG1 Antibodies)).
These results implied that AngII could effectively induce EpiCs to differentiate into vascular smooth muscle-like cells through the AT1 receptor (show AGTRAP Antibodies).
Results suggest the involvement of angiotensin II (Ang II), through its angiotensin type-1 receptor (AT1R (show AGTRAP Antibodies)) in the inflammation induced by Aah (show ASPH Antibodies) venom, in the heart and the aorta.
Angiotensin II stimulates PYY secretion, in turn inhibiting epithelial anion fluxes, thereby reducing net fluid secretion into the colonic lumen.
expression of spinal ACE (show ACE Antibodies) increased in streptozotocin-induced diabetic mice, which in turn led to an increase in Ang II levels and tactile allodynia.
NADPH oxidase (show NOX1 Antibodies) plays an important role in proMMP-2 expression and activation and MMP-2 (show MMP2 Antibodies) mediated SMC (show DYM Antibodies) proliferation occurs through the involvement of Spm (show NPC1 Antibodies)-Cer (show CBLN1 Antibodies)-S1P (show MBTPS1 Antibodies) signaling axis under ANG II stimulation of PASMCs
The metabolism of angiotensin II (Ang II) to angiotensin III (Ang III) and its role in the vasorelaxation response in adrenal arteries are reported.
The study identified the serine phosphorylation (p-Ser (show SIGLEC1 Antibodies)) sites induced by PKC-Beta (show PRKCB Antibodies) activation or AGT, which inhibits insulin (show INS Antibodies)-induced p-Tyr (show TYR Antibodies) sites on IRS2 (show IRS2 Antibodies) and its signals in endothelial cells.
Data suggest up-regulation of AGT in granulosa cells and of Ang II in follicular fluid during preovulatory period; Ang II appears to amplify stimulatory effects of luteinizing hormone on secretion of progesterone/prostaglandins by granulosa cells.
Data suggest that angiotensin II promotes uptake/accumulation of iron (non-transferrin (show Tf Antibodies) bound iron) into vascular endothelial cells; such iron accumulation appears to depend on activation of angiotensin type 1 receptor and promotes oxidative stress.
a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl.
The objective of this study was to characterize the profiles of Ang-(1-7), MAS receptor, ACE(2), NEP and PEP during the ovulatory process in cattle.
Fetal adrenal cells in primary culture respond to angiotensin-II by increasing aldosterone production and aldosterone synthase (show CYP11B2 Antibodies) [P450c18/CYP11B2 (show CYP11B2 Antibodies)] activity.
ANG II inhibits bTREK-1 K(+) channels by a Ca(2+)-dependent mechanism that does not require the depletion of membrane-associated PIP(2).
prostaglandin F2alpha, endothelin-1 (show EDN1 Antibodies), and angiotensin II may interact with each other in a local positive feedback manner to activate their secretion in the regressing corpus luteum, thus accelerating and completing luteolysis
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
alpha-1 antiproteinase, antitrypsin
, angiotensin I
, angiotensin II
, serine (or cysteine) proteinase inhibitor
, serpin A8
, angiotensin ll
, angiotensinogen (PAT)
, zC8A9.1 (angiotensinogen )
, Serpin A8
, alanine--glyoxylate aminotransferase
, angiotensin receptor 2
, serine--pyruvate aminotransferase, mitochondrial
, serine--pyruvate aminotransferase, peroxisomal
, serine-pyruvate aminotransferase
, serine:pyruvate aminotransferase SPT
, serine:pyruvate/alanine:glyoxylate aminotransferase
, 6-O-methylguanine-DNA methyltransferase
, O-6-alkylguanine-DNA alkyltransferase
, methylated-DNA--protein-cysteine methyltransferase