AGT antibody (AA 376-485)

Catalog No. ABIN559812

Cited in 2+ publications. The Mouse Monoclonal anti-AGT antibody (Clone 1A10) (ABIN559812) specifically detects AGT in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for AGT antibody (AA 376-485) (ABIN559812)

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AGT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1A10

Product Details anti-AGT Antibody

Binding Specificity: AA 376-485

Purpose: Mouse monoclonal antibody raised against a partial recombinant AGT.

Sequence: TIHLTMPQLV LQGSYDLQDL LAQAELPAIL HTELNLQKLS NDRIRVGEVL NSIFFELEAD EREPTESTQQ LNKPEVLEVT LNRPFLFAVY DQSATALHFL GRVANPLSTA

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: AGT (AAH11519, 376 a.a. ~ 485 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-AGT antibody (ABIN559812)

Jain, Vinukonda, Fiering, Kumar: "A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice compared with -217G." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 295, Issue 6, pp. R1849-57, (2008) (PubMed).

Jain, Li, Patil, Kumar: "HNF-1alpha plays an important role in IL-6-induced expression of the human angiotensinogen gene." in: American journal of physiology. Cell physiology, Vol. 293, Issue 1, pp. C401-10, (2007) (PubMed).

Target Details for AGT

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Alternative Name: AGT

Background: Full Gene Name: angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Synonyms: ANHU,FLJ92595,FLJ97926,SERPINA8

Gene ID: 183

Pathways: JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity