Caspase 1 ELISA Kit
(1 reference)Quick Overview for Caspase 1 ELISA Kit (ABIN1168983)
Target
See all Caspase 1 (CASP1) ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
Sample Type
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Minimum Detection Limit
- 0.15 ng/mL
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Analytical Method
- Quantitative
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Specificity
- Detects mouse caspase-1 (proform as well as p10 and p20 domain).
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Cross-Reactivity
- Mouse (Murine)
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Cross-Reactivity (Details)
- Does not detect human caspase-1.
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Sensitivity
- 33 pg/mL
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Characteristics
- Standards are full lenght proteins.
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Caspase 1 (CASP1) ELISA Kit
CASP1 Reactivity: Human Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Cell Lysate, Tissue Homogenate
Caspase 1 (CASP1) ELISA KitCASP1 Reactivity: Rat Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Lysate, Tissue Homogenate
Caspase 1 (CASP1) ELISA KitCASP1 Reactivity: Human Colorimetric Sandwich ELISA 78.125 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
Caspase 1 (CASP1) ELISA KitCASP1 Reactivity: Rat Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Plasma, Serum, Tissue Homogenate
Caspase 1 (CASP1) ELISA KitCASP1 Reactivity: Rat Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Plasma, Serum
Caspase 1 (CASP1) ELISA KitCASP1 Reactivity: Mouse Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Caspase 1 (CASP1) ELISA KitSmall Sample CASP1 Reactivity: Mouse Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Handling Advice
- Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use.
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Storage
- 4 °C
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Storage Comment
- After standard reconstitution prepare aliquots and store at -20°C.
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Expiry Date
- 12 months
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: "Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice." in: The American journal of pathology, Vol. 183, Issue 1, pp. 96-107, (2013) (PubMed).
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: "Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice." in: The American journal of pathology, Vol. 183, Issue 1, pp. 96-107, (2013) (PubMed).
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- Caspase 1 (CASP1)
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Alternative Name
- Caspase-1
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Background
- Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals._x000D__x000D_This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.
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UniProt
- P29452
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Pathways
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
Target See all Caspase 1 (CASP1) ELISA Kits
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