APP ELISA Kit
Quick Overview for APP ELISA Kit (ABIN2042350)
Target
See all APP ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
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Minimum Detection Limit
- 2 pg/mL
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Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Sensitivity
- < 10 pg/mL
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Components
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96-well plate pre-coated with anti-APP, Human
Lyophilized recombinant APP, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Amyloid beta (A4) Precursor Protein (APP) ELISA Kit
APP Reactivity: Human Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Cerebrospinal Fluid, Plasma, Serum
Amyloid beta (A4) Precursor Protein (APP) ELISA KitWide Range APP Reactivity: Human Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Cerebrospinal Fluid, Plasma, Serum
Amyloid beta (A4) Precursor Protein (APP) ELISA KitAPP Reactivity: Mouse Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate
Amyloid beta (A4) Precursor Protein (APP) ELISA KitWide Range APP Reactivity: Rat Colorimetric Sandwich ELISA 1.25 ng/mL - 80 ng/mL Plasma, Serum, Tissue Homogenate
Amyloid beta (A4) Precursor Protein (APP) ELISA KitAPP Reactivity: Rat Colorimetric Sandwich ELISA 78.12 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
Amyloid beta (A4) Precursor Protein (APP) ELISA KitAPP Reactivity: Human Colorimetric Sandwich ELISA 0.25-16 ng/mL Cell Culture Cells, Plasma, Serum
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Plate
- Pre-coated
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Protocol
- Sandwich ELISA quantitative detection kit for Human APP in cell culture supernates, serum and plasma (heparin, EDTA).Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid (A ), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. APP undergoes posttranslational proteolytic processing by alpha-, beta-, and gamma-secretases. Alpha-secretase generates soluble amyloid protein, while beta- and gamma-secretases generate APP components with amyloidogenic features. These 2 processing pathways are mutually exclusive.
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Restrictions
- For Research Use only
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Storage
- 4 °C/-20 °C
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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Alternative Name
- APP
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Gene ID
- 351
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UniProt
- P05067
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Pathways
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
Target See all APP ELISA Kits
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