CD40 ELISA Kit
Quick Overview for CD40 ELISA Kit (ABIN2042400)
Target
See all CD40 ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
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Minimum Detection Limit
- 15.6 pg/mL
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Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Sensitivity
- < 1 pg/mL
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Components
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96-well plate pre-coated with anti-CD40/TNFRSF5, Human
Lyophilized recombinant CD40/TNFRSF5, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Plate
- Pre-coated
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Protocol
- Sandwich ELISA quantitative detection kit for Human CD40 in cell culture supernates, serum, plasma ( eparin, EDTA), saliva, urine and human milk.CD40 is a cell surface receptor that is expressed on the surface of all mature B cells, most mature B-cell malignancies, and some early B-cell acute lymphocytic leukemias, but is not expressed on plasma cells.1The CD40 gene is localized to the long arm of chromosome 20, bands q12-q13.2.2The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.3
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Restrictions
- For Research Use only
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Storage
- 4 °C/-20 °C
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- CD40
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Alternative Name
- CD40/TNFRSF5
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Gene ID
- 958
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UniProt
- P25942
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Pathways
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target See all CD40 ELISA Kits
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