CXCL10 ELISA Kit
Quick Overview for CXCL10 ELISA Kit (ABIN2042422)
Target
See all CXCL10 ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
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Minimum Detection Limit
- 31.2 pg/mL
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Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Sensitivity
- < 1 pg/mL
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Components
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96-well plate pre-coated with anti-CXCL10/IP-10, Mouse
Lyophilized recombinant CXCL10/IP-10, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Plate
- Pre-coated
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Protocol
- Sandwich ELISA quantitative detection kit for Mouse CXCL10/IP-10 in cell culture supernates, serum and plasma (heparin).Chemokine (C-X-C motif) ligand 10 (CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10kD interferon-gamma-induced protein ( -IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN- . These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis.It is a potent inhibitor of angiogenesis in vivo. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. It is a RAS target gene and is overexpressed in the majority of colorectal cancers.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3.
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Restrictions
- For Research Use only
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Storage
- 4 °C/-20 °C
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- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
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Alternative Name
- CXCL10/IP-10
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Gene ID
- 15945
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UniProt
- P17515
Target See all CXCL10 ELISA Kits
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