IL-33 ELISA Kit

Catalog No. ABIN2042550

This Human IL-33 ELISA Kit is a Colorimetric ELISA Kit designed to quantify Human IL-33.

Quick Overview for IL-33 ELISA Kit (ABIN2042550)

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Reactivity: Human

Detection Method: Colorimetric

Method Type: Competition ELISA

Detection Range: 15.6-1000 pg/mL

Application: ELISA

Product Details IL-33 ELISA Kit

Minimum Detection Limit: 15.6 pg/mL

Brand: BioAssay™

Cross-Reactivity (Details): No detectable crossreactivity with other relevant proteins

Sensitivity: < 10 pg/mL

Components: A: Microtiter Strip, 1x96 wells
B: IL-33 Standard, 2x10 ng
C: Anti-human IL-33 (Biotin), 130 µL

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

Target Details for IL-33

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Alternative Name: IL-33

Background: Interleukin 33 (IL-33) is a cytokine belonging to the IL-1 superfamily. The IL33 gene maps to chromosome 9p24.1 by using of genomic database analysis. Recombinant mature human IL33 bound to ST2. The induction of type 2 cytokines by IL-33 in vivo is believed to induce the severe pathological changes observed in mucosal organs following administration of IL-33. IL33, an alarmin released from necrotic cells, is necessary for potent CD8 + T cell (CTL) responses to replicating, prototypic RNA, and DNA viruses in mice. IL33 prevented the downregulation of CXCR2 and inhibition of chemotaxis induced by activation of TLR4, and found that IL33 reverses the TLR4-induced reduction of CXCR2 expression via the inhibition of expression of GRK2.

Pathways: Production of Molecular Mediator of Immune Response