Kallikrein 5 ELISA Kit

Catalog No. ABIN2042572

Human Kallikrein 5 ELISA Kit Colorimetric assay for quantification of Human Kallikrein 5.

Quick Overview for Kallikrein 5 ELISA Kit (ABIN2042572)

Target: Kallikrein 5 (KLK5)

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 8-5000 pg/mL

Application: ELISA

Product Details Kallikrein 5 ELISA Kit

Minimum Detection Limit: 8 pg/mL

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivity: < 10 pg/mL

Components: 96-well plate pre-coated with anti-KLK5, Human
Lyophilized recombinant KLK5, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Application Details

Plate: Pre-coated

Protocol: Sandwich ELISA quantitative detection kit for Human KLK5 in cell culture supernates, serum, plasma (heparin, EDTA) human milk and saliva.Kallikrein gene 5 (KLK5, also known as KLK-L2), located on chromosome 19q13.4, is one of the newly identified members of the kallikrein gene family, which is a subgroup of the serine protease enzyme family. In normal human tissues, KLK5 is highly expressed in skin, mammary gland and testis. KLK5 has been suggested to regulate cell shedding (desquamation) in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. It is proposed that KLK5 regulates this process since it is able to self-activate in addition to activating KLK7 and KLK14.

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

Target Details for Kallikrein 5

Target: Kallikrein 5 (KLK5)

Alternative Name: KLK5

Gene ID: 25818

UniProt: Q9Y337

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling