Neurotrophin 3 ELISA Kit

Catalog No. ABIN2042618

This Colorimetric ELISA kit is designed for the quantitative measurement of Rat Neurotrophin 3.

Quick Overview for Neurotrophin 3 ELISA Kit (ABIN2042618)

Target: Neurotrophin 3 (NTF3)

Reactivity: Rat

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 15.6-1000 pg/mL

Application: ELISA

Product Details Neurotrophin 3 ELISA Kit

Minimum Detection Limit: 15.6 pg/mL

Cross-Reactivity (Details): There is cross-reactivates with NT-4 <2.5 % , and no detectable cross-reactivity with any other cytokine.

Sensitivity: < 2 pg/mL

Components: 96-well plate pre-coated with anti-Neurotrophin-3, Rat
Lyophilized recombinant Neurotrophin-3, Rat standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Application Details

Plate: Pre-coated

Protocol: Sandwich ELISA quantitative detection kit for Rat Neurotrophin-3 in cell culture supernates and serum.Neurotrophin-3 (NT-3) is a new member of the nerve growth factor gene family, which plays an important role in the development and maintenance of the vertebrate nervous system.1 NT-3 and its receptor, called neurotrophic tyrosine kinase receptor type 3 (Ntrk3, also called TrkC), are expressed early and throughout embryogenesis.2 NT-3 is one of five neurotrophin growth factors which shape the development of the nervous system by regulating neuronal survival and differentiation.3 NT-3 may be one of the central nervous system-derived factors that mediate neural crest (NC) cell proliferation in vivo.4 NT-3 has been mapped to human chromosome 12p and mouse chromosome 6.1

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

Target Details for Neurotrophin 3

Target: Neurotrophin 3 (NTF3)

Alternative Name: Neurotrophin-3

Gene ID: 81737

UniProt: P18280

Pathways: RTK Signaling, Neurotrophin Signaling Pathway