TIMP3 ELISA Kit
Quick Overview for TIMP3 ELISA Kit (ABIN2042683)
Target
See all TIMP3 ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
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Minimum Detection Limit
- 6 pg/mL
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Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Sensitivity
- < 2 pg/mL
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Components
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96-well plate pre-coated with anti-TIMP-3, Human
Lyophilized recombinant TIMP-3, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Plate
- Pre-coated
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Protocol
- Sandwich ELISA quantitative detection kit for Human TIMP-3 in cell culture supernates, serum, plasma (heparin, EDTA) and saliva.The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy (SFD).
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Restrictions
- For Research Use only
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Storage
- 4 °C/-20 °C
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- TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
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Alternative Name
- TIMP-3
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Gene ID
- 7078
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UniProt
- P35625
Target See all TIMP3 ELISA Kits
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