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TIMP3 ELISA Kit

Human TIMP3 ELISA Kit, Colorimetric assay for quantification of Human TIMP3.
Catalog No. ABIN2042683
$1,092.50
Plus shipping costs $50.00
96 tests
Shipping to: United States
Delivery in 16 to 21 Business Days

Quick Overview for TIMP3 ELISA Kit (ABIN2042683)

Target

See all TIMP3 ELISA Kits
TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Reactivity

  • 9
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Detection Range

6-10000 pg/mL

Application

ELISA
  • Minimum Detection Limit

    6 pg/mL

    Cross-Reactivity (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensitivity

    < 2 pg/mL

    Components

    96-well plate pre-coated with anti-TIMP-3, Human
    Lyophilized recombinant TIMP-3, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plate

    Pre-coated

    Protocol

    Sandwich ELISA quantitative detection kit for Human TIMP-3 in cell culture supernates, serum, plasma (heparin, EDTA) and saliva.The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy (SFD).

    Restrictions

    For Research Use only
  • Storage

    4 °C/-20 °C
  • Target See all TIMP3 ELISA Kits

    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

    Alternative Name

    TIMP-3

    Gene ID

    7078

    UniProt

    P35625
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