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TIMP3 ELISA Kit

Human TIMP3 ELISA Kit Colorimetric assay for quantification of Human TIMP3.
Catalog No. ABIN2042683

Quick Overview for TIMP3 ELISA Kit (ABIN2042683)

Target

See all TIMP3 ELISA Kits
TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Reactivity

  • 9
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Detection Range

6-10000 pg/mL

Application

ELISA
  • Minimum Detection Limit

    6 pg/mL

    Cross-Reactivity (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensitivity

    < 2 pg/mL

    Components

    96-well plate pre-coated with anti-TIMP-3, Human
    Lyophilized recombinant TIMP-3, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plate

    Pre-coated

    Protocol

    Sandwich ELISA quantitative detection kit for Human TIMP-3 in cell culture supernates, serum, plasma (heparin, EDTA) and saliva.The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy (SFD).

    Restrictions

    For Research Use only
  • Storage

    4 °C/-20 °C
  • Target See all TIMP3 ELISA Kits

    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

    Alternative Name

    TIMP-3

    Gene ID

    7078

    UniProt

    P35625
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