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CXCL2 ELISA Kit

CXCL2 Reactivity: Rat Colorimetric Cell Culture Cells, Plasma, Serum
Catalog No. ABIN2648786
  • Target See all CXCL2 ELISA Kits
    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
    Reactivity
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    • 2
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    Rat
    Detection Method
    Colorimetric
    Application
    ELISA
    Purpose
    Rat Macrophage inflammatory protein-2 (MIP-2) ELISA Assay Kit (enzyme-linked immunoassay kit) is intended for the quantitative determination of rat macrophage inflammatory protein-2 (MIP-2 ) concentrations in cell culture supernates, serum, and plasma.
    Sample Type
    Serum, Plasma, Cell Culture Cells
    Analytical Method
    Quantitative
    Characteristics
    Rat Macrophage inflammatory protein-2 (MIP-2) ELISA Assay Kit is for research use only and not to be used in diagnostic procedures.
    Top Product
    Discover our top product CXCL2 ELISA Kit
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Assay Time
    3.5 h
    Plate
    Pre-coated
    Protocol
    Macrophage inflammatory protein-2(MIP-2) was originally identified as a heparin binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The protein is produced by a variety of cell types, including intestinal epithelium, macrophages, astrocytes and fibroblasts. Homologs of the mouse MIP-2 have been identified in human, rat and cotton rat. MIP-2 is an ELR-containing member of the alpha (CXC) subfamily of chemokines. The cotton rat MIP-2 gene encodes a 101 amino acid (aa) residue precursor protein with a 28 aa putative signal peptide that is cleaved to generate the 73 aa mature protein. Mature cotton rat MIP-2 has two intrachain disulfide bonds and no potential glycosylation sites. It shares approximately 79 % and 85 % aa sequence identity with rat CINC-3 and mouse MIP-2, respectively. MIP-2 is a potent neutrophil attractant and activator. MIP-2 binds and activates the chemokine receptor CXCR-2. The recombinant cotton rat MIP-2 has been shown to bind and activate the human CXCR-2.
    Restrictions
    For Research Use only
  • Storage
    4 °C
  • Target See all CXCL2 ELISA Kits
    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
    Alternative Name
    MIP-2 (CXCL2 Products)
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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