Granulin ELISA Kit
Quick Overview for Granulin ELISA Kit (ABIN2745482)
Target
See all Granulin (GRN) ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
Sample Type
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Minimum Detection Limit
- 0.125 ng/mL
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Analytical Method
- Quantitative
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Specificity
- Detects mouse progranulin.
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Cross-Reactivity
- Mouse (Murine)
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No Cross-Reactivity
- Human
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Cross-Reactivity (Details)
- Does not cross-react with human progranulin.
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Sensitivity
- 60 pg/mL
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Characteristics
- Progranulin (mouse) ELISA Kit
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Granulin (GRN) ELISA Kit
GRN Reactivity: Human Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Granulin (GRN) ELISA KitGRN Reactivity: Mouse Colorimetric Competition ELISA 0.469 ng/mL - 30 ng/mL Plasma, Serum, Tissue Homogenate
Granulin (GRN) ELISA KitGRN Reactivity: Mouse Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Granulin (GRN) ELISA KitGRN Reactivity: Rat Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Granulin (GRN) ELISA KitGRN Reactivity: Human AA 18-593 Colorimetric Sandwich ELISA 1.56-100 ng/mL Cell Culture Supernatant, Milk, Plasma (EDTA), Plasma (heparin), Saliva, Serum, Urine
Granulin (GRN) ELISA KitGRN Reactivity: Mouse AA 18-589 Colorimetric Sandwich ELISA 0.78-50 ng/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Granulin (GRN) ELISA KitGRN Reactivity: Human Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Breast Milk, Cell Culture Supernatant, Plasma (EDTA - heparin), Saliva, Serum, Urine
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Storage
- 4 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: +4°C
12 months after the day of manufacturing. See expiry date on ELISA Kit box.
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- Granulin (GRN)
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Alternative Name
- Progranulin
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Target Type
- Viral Protein
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Background
- Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimer's disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
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UniProt
- P28798
Target See all Granulin (GRN) ELISA Kits
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