IL-25 ELISA Kit
Quick Overview for IL-25 ELISA Kit (ABIN4986951)
Target
See all IL-25 (IL25) ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
Sample Type
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Minimum Detection Limit
- 0.03 ng/mL
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Analytical Method
- Quantitative
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Specificity
- Natural and recombinant Mouse IL-25(IL-17E) Ligand
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Sensitivity
- 15 pg/mL
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Material not included
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
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Application Notes
- Detection Wavelength: 450 nm
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Sample Volume
- 20 μL
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Assay Time
- 3 h
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Storage
- 4 °C
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- IL-25 (IL25) (Interleukin 25 (IL25))
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Alternative Name
- IL-25(IL-17E)
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Background
- IL-25 (also known as IL-17E) is a member of the IL-17 family of proinflammatory cytokines, which includes IL-17A, IL-17B, IL-17C, IL-17F and IL-17A/F. IL-17E is found at low levels in various peripheral tissues. It is a proinflammatory cytokine that promotes airway eosinophilia in mice. IL-17E plays a role in Th2 type inflammatory diseases, such as asthma and atopic dermatitis. IL-25 induces elevatedgene expression of IL-4, IL-5 and IL-13 in multiple tissues and results in T helper 2 (TH2)-type immune responses (increased serumIgE levels) and pathologic changes in the lungsand digestive tract with eosinophilic infiltrates, increased mucusproduction, epithelial cell hyperplasia and overall amplified allergicinflammation. IL-25 shares the receptor IL-17RB with IL-17B, although it binds with much higher affinity than IL-17B.
Target See all IL-25 (IL25) ELISA Kits
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