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IL-25 ELISA Kit

This Mouse IL-25 ELISA Kit is a Colorimetric ELISA Kit designed to quantify Mouse IL-25.
Catalog No. ABIN4986951

Quick Overview for IL-25 ELISA Kit (ABIN4986951)

Target

See all IL-25 (IL25) ELISA Kits
IL-25 (IL25) (Interleukin 25 (IL25))

Reactivity

  • 8
  • 4
  • 3
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Mouse

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Detection Range

0.03-2.0 ng/mL

Application

ELISA

Sample Type

Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
  • Minimum Detection Limit

    0.03 ng/mL

    Analytical Method

    Quantitative

    Specificity

    Natural and recombinant Mouse IL-25(IL-17E) Ligand

    Sensitivity

    15 pg/mL

    Material not included

    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
  • Application Notes

    Detection Wavelength: 450 nm

    Sample Volume

    20 μL

    Assay Time

    3 h

    Plate

    Pre-coated

    Restrictions

    For Research Use only
  • Storage

    4 °C
  • Target See all IL-25 (IL25) ELISA Kits

    IL-25 (IL25) (Interleukin 25 (IL25))

    Alternative Name

    IL-25(IL-17E)

    Background

    IL-25 (also known as IL-17E) is a member of the IL-17 family of proinflammatory cytokines, which includes IL-17A, IL-17B, IL-17C, IL-17F and IL-17A/F. IL-17E is found at low levels in various peripheral tissues. It is a proinflammatory cytokine that promotes airway eosinophilia in mice. IL-17E plays a role in Th2 type inflammatory diseases, such as asthma and atopic dermatitis. IL-25 induces elevatedgene expression of IL-4, IL-5 and IL-13 in multiple tissues and results in T helper 2 (TH2)-type immune responses (increased serumIgE levels) and pathologic changes in the lungsand digestive tract with eosinophilic infiltrates, increased mucusproduction, epithelial cell hyperplasia and overall amplified allergicinflammation. IL-25 shares the receptor IL-17RB with IL-17B, although it binds with much higher affinity than IL-17B.
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