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IGF2 ELISA Kit

This Colorimetric ELISA kit is designed for the quantitative measurement of Hamster IGF2.
Catalog No. ABIN5510551

Quick Overview for IGF2 ELISA Kit (ABIN5510551)

Target

See all IGF2 ELISA Kits
IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Binding Specificity

AA 25-91

Reactivity

  • 9
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Hamster

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Application

ELISA
  • Purpose

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Chinese hamster IGF-2

    Brand

    PicoKine™

    Analytical Method

    Quantitative

    Specificity

    Expression system for standard: E.coli
    Immunogen sequence: A25-E91

    Cross-Reactivity (Details)

    There is no detectable cross-reactivity with IGF-1.

    Characteristics

    Sequence similarities: Belongs to the insulin family.

  • Plate

    Pre-coated

    Restrictions

    For Research Use only
  • Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    Expiry Date

    12 months
  • Target See all IGF2 ELISA Kits

    IGF2 (Insulin-Like Growth Factor 2 (IGF2))

    Alternative Name

    Igf2

    Background

    Protein Function: The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.

    Background: Insulin-like growth factor II is also known as somatomedin A. IGF-2 is a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is paternally expressed in the fetus and placenta. IGF-II is a mitogen for many cell types and an important modulator of muscle growth and differentiation. IGF-II gene is prevalently expressed during prenatal development and its gene activity is regulated by genomic imprinting, in that the allele inherited from the father is active and the allele inherited from the mother is inactive in most normal tissues. IGF-II appears to be induced by placental lactogen during prenatal development. It is a mediator of prolactin-induced alveologenesis, prolactin, IGF-2, and cyclin D1, all of which are overexpressed in breast cancers, are components of a developmental pathway in the mammary gland.

    Synonyms: Insulin-like growth factor II,IGF-II,Multiplication-stimulating activity,MSA,Multiplication-stimulating polypeptide,Insulin-like growth factor II,Preptin,Igf2,Igf-2,

    Full Gene Name: Insulin-like growth factor II

    Cellular Localisation: Secreted.

    UniProt

    P01346

    Pathways

    Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
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