TIMP3 ELISA Kit
Quick Overview for TIMP3 ELISA Kit (ABIN5510570)
Target
See all TIMP3 ELISA KitsBinding Specificity
Reactivity
Detection Method
Method Type
Application
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Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of horse equine TIMP-3
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Brand
- PicoKine™
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Analytical Method
- Quantitative
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Specificity
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Expression system for standard: NSO
Immunogen sequence: C24-P211 -
Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Characteristics
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Sequence similarities: Belongs to the protease inhibitor I35 (TIMP) family.
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TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA Kit
TIMP3 Reactivity: Human Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA KitTIMP3 Reactivity: Mouse Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA KitTIMP3 Reactivity: Rat Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA KitTIMP3 Reactivity: Human Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Plasma, Serum
TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA KitTIMP3 Reactivity: Rabbit Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate
TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA KitTIMP3 Reactivity: Chicken Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA KitTIMP3 Reactivity: Pig Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA KitTIMP3 Reactivity: Cow Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA KitTIMP3 Reactivity: Horse Colorimetric Sandwich ELISA 0.47 ng/mL - 30 ng/mL Plasma, Serum, Tissue Homogenate
TIMP Metallopeptidase Inhibitor 3 (TIMP3) ELISA KitTIMP3 Reactivity: Goat Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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Expiry Date
- 12 months
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- TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
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Alternative Name
- TIMP3
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Background
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Protein Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
Background: The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD).
Synonyms: Metalloproteinase inhibitor 3,Protein MIG-5,Tissue inhibitor of metalloproteinases 3,TIMP-3,TIMP3,
Full Gene Name: Metalloproteinase inhibitor 3
Cellular Localisation: Secreted, extracellular space, extracellular matrix. -
UniProt
- P35625
Target See all TIMP3 ELISA Kits
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