SPINT2 ELISA Kit

Catalog No. ABIN5510589

Mouse SPINT2 ELISA Kit, Colorimetric assay for quantification of Mouse SPINT2.

Quick Overview for SPINT2 ELISA Kit (ABIN5510589)

Target: SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

Binding Specificity: AA 30-140

Reactivity: Mouse

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Product Details SPINT2 ELISA Kit

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse HAI-2/SPINT2

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO
Immunogen sequence: R30-K140

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Isoform 2 is more predominantly expressed than isoform 1.

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for SPINT2

Target: SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

Alternative Name: Spint2

Background:

Protein Function: Inhibitor of HGF activator.

Background: Kunitz-type protease inhibitor 2 is an enzyme inhibitor that in humans is encoded by the SPINT2 gene. This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. And this gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: Kunitz-type protease inhibitor 2,Hepatocyte growth factor activator inhibitor type 2,HAI-2,Spint2,Hai2,

Full Gene Name: Kunitz-type protease inhibitor 2

Cellular Localisation: Membrane, Single-pass type I membrane protein.

UniProt: Q9WU03