Thrombospondin 1 ELISA Kit

Catalog No. ABIN5510594

This Monkey Thrombospondin 1 ELISA Kit is a Colorimetric ELISA Kit designed to quantify Monkey Thrombospondin 1.

Quick Overview for Thrombospondin 1 ELISA Kit (ABIN5510594)

Target: Thrombospondin 1 (THBS1)

Binding Specificity: AA 19-1170

Reactivity: Monkey

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Product Details Thrombospondin 1 ELISA Kit

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate THBS1/TSP1

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO
Immunogen sequence: N19-P1170

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Sequence similarities: Belongs to the thrombospondin family.

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for Thrombospondin 1

Target: Thrombospondin 1 (THBS1)

Alternative Name: THBS1

Background:

Protein Function: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity). .

Background: Thrombospondin 1, also known as THBS1, is a protein that in humans in encoded by the THBS1 gene. Thrombospondin 1 is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. By in situ hybridization, the THBS1 gene was mapped to monkey primate 15q15 and the cognate gene to monkey primate chromosome 2(region F) and was localized to 15q11-qter by Southern analysis of human-rodent somatic cell hybrids. Thrombospondin I is a multimodular secreted protein that associates with the extracellular matrix and possesses a variety of biologic functions, including a potent antiangiogenic activity. Other thrombospondin genes include thrombospondins II, III, and IV.

Synonyms: Thrombospondin-1,THBS1,TSP, TSP1,

Full Gene Name: Thrombospondin-1

Cellular Localisation: Endoplasmic reticulum . Sarcoplasmic reticulum.

UniProt: P07996

Pathways: Autophagy