CCL25 ELISA Kit

Catalog No. ABIN5510634

Mouse CCL25 ELISA Kit Colorimetric assay for quantification of Mouse CCL25.

Quick Overview for CCL25 ELISA Kit (ABIN5510634)

Target: CCL25 (Chemokine (C-C Motif) Ligand 25 (CCL25))

Binding Specificity: AA 24-144

Reactivity: Mouse

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Product Details CCL25 ELISA Kit

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse CCL25/TECK

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: E.coli
Immunogen sequence: Q24-N144

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for CCL25

Target: CCL25 (Chemokine (C-C Motif) Ligand 25 (CCL25))

Alternative Name: Ccl25

Background:

Protein Function: Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

Background: Chemokine (C-C motif) ligand 25 (CCL25) is a small cytokine belonging to the CC chemokine family that is also known as TECK (Thymus-Expressed Chemokine). The mouse Teck gene was mapped to chromosome 8 and human Teck gene was to 19p13.2. CCL25 is believed to play a role in the development of T-cells. It is chemotactic for thymocytes, macrophages, and dendritic cells. CCL25 elicits its effects by binding to the chemokine receptor CCR9.

Synonyms: C-C motif chemokine 25,Chemokine TECK,Small-inducible cytokine A25,Thymus-expressed chemokine,Ccl25,Scya25, Teck,

Full Gene Name: C-C motif chemokine 25

Cellular Localisation: Secreted.

UniProt: O35903