SFRP5 ELISA Kit

Catalog No. ABIN5510652

Rabbit SFRP5 ELISA Kit Colorimetric assay for quantification of Rabbit SFRP5.

Quick Overview for SFRP5 ELISA Kit (ABIN5510652)

Target: SFRP5 (Secreted Frizzled-Related Protein 5 (SFRP5))

Binding Specificity: AA 30-317

Reactivity: Rabbit

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Product Details SFRP5 ELISA Kit

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of rabbit SFRP5

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: CHO
Immunogen sequence: E30-H317

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle. .

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for SFRP5

Target: SFRP5 (Secreted Frizzled-Related Protein 5 (SFRP5))

Alternative Name: SFRP5

Background:

Protein Function: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.

Background: Secreted frizzled-related protein 5 is a protein that in humans is encoded by the SFRP5 gene. SFRP5 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.

Synonyms: Secreted frizzled-related protein 5,sFRP-5,Frizzled-related protein 1b,FRP-1b,Secreted apoptosis-related protein 3,SARP-3,SFRP5,FRP1B, SARP3,

Full Gene Name: Secreted frizzled-related protein 5

Cellular Localisation: Secreted.

UniProt: Q5T4F7

Pathways: WNT Signaling