LRIG3 ELISA Kit

Catalog No. ABIN5510668

This Colorimetric ELISA kit is designed for the quantitative measurement of Human LRIG3.

Quick Overview for LRIG3 ELISA Kit (ABIN5510668)

Target: LRIG3 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 3 (LRIG3))

Binding Specificity: AA 28-807

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Product Details LRIG3 ELISA Kit

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human LRIG3

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO
Immunogen sequence: D28-T807

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Widely expressed. .

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for LRIG3

Target: LRIG3 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 3 (LRIG3))

Alternative Name: LRIG3

Background:

Protein Function: May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity). .

Background: LRIG3 is a 1,119-amino acid protein that contains a signal peptide. This gene is mapped to chromosome 12q13.2. Northern blot analysis detected a 5.1-kb LRIG3 transcript in all tissues analyzed. Quantitative RT-PCR detected highest expression in stomach and lowest expression in blood. And quantitative RT-PCR of mouse tissues revealed ubiquitous expression, but the pattern of expression differed from that in human tissues. LRIG3 may play a role in craniofacial and inner ear morphogenesis during embryonic development. In addition, it may act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1.

Synonyms: Leucine-rich repeats and immunoglobulin-like domains protein 3,LIG-3,LRIG3,LIG3,UNQ287/PRO326/PRO335,

Full Gene Name: Leucine-rich repeats and immunoglobulin-like domains protein 3

Cellular Localisation: Cell membrane, Single-pass type I membrane protein . Cytoplasmic vesicle membrane, Single-pass type I membrane protein . Detected in cytoplasmic vesicles when coexpressed with ERBB4..

UniProt: Q6UXM1