IGDCC4 ELISA Kit

Catalog No. ABIN5510687

This Mouse IGDCC4 ELISA Kit is a Colorimetric ELISA Kit designed to quantify Mouse IGDCC4.

Quick Overview for IGDCC4 ELISA Kit (ABIN5510687)

Target: IGDCC4 (Immunoglobulin Superfamily, DCC Subclass, Member 4 (IGDCC4))

Binding Specificity: AA 25-954

Reactivity: Mouse

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Product Details IGDCC4 ELISA Kit

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse NOPE/IGDCC4

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO
Immunogen sequence: E25-H954

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Expressed in skeletal muscle, heart and brain. Brain expression is hippocampus-specific. .

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for IGDCC4

Target: IGDCC4 (Immunoglobulin Superfamily, DCC Subclass, Member 4 (IGDCC4))

Alternative Name: Igdcc4

Background:

Background: IGDCC4, also known as NOPE, plays essential roles in biologic functions of the cell surface, including cell adhesion, cell migration, and signal transduction. NOPE is identified as an oncofetal marker of murine and human hepatocellular carcinoma (HCC). Its expression is elevated in mouse and human hepatoma cell lines and in mouse hepatomas, but it is not expressed in normal liver or preneoplastic mouse HCC. Furthermore, NOPE is expressed in both AFP -positive and -negative tumors and is specifically expressed in epithelial tumor cells.

Synonyms: Immunoglobulin superfamily DCC subclass member 4,Neighbor of punc e11,Protein DDM36,Igdcc4,Ddm36, Kiaa1628, Nope,

Full Gene Name: Immunoglobulin superfamily DCC subclass member 4

Cellular Localisation: Cell membrane, Single-pass type I membrane protein.

UniProt: Q9EQS9