TREML1 ELISA Kit

Catalog No. ABIN5510688

Human TREML1 ELISA Kit Colorimetric assay for quantification of Human TREML1.

Quick Overview for TREML1 ELISA Kit (ABIN5510688)

Target: TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))

Binding Specificity: AA 16-162

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Product Details TREML1 ELISA Kit

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human TREML1

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO
Immunogen sequence: Q16-P162

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Detected in platelets, monocytic leukemia and in T-cell leukemia. .

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for TREML1

Target: TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))

Alternative Name: TREML1

Background:

Protein Function: Cell surface receptor that may play a role in the innate and adaptive immune response. .

Background: Trem-like transcript 1 protein is a protein that in humans is encoded by the TREML1 gene. This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. This protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants.

Synonyms: Trem-like transcript 1 protein,TLT-1,Triggering receptor expressed on myeloid cells-like protein 1,TREML1,TLT1,UNQ1825/PRO3438,

Full Gene Name: Trem-like transcript 1 protein

Cellular Localisation: Cell membrane, Single-pass type I membrane protein . Cytoplasm . Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151). Transported to the cell surface after stimulation by thrombin (PubMed:15100151). Soluble fragments can be released into the serum by proteolysis (PubMed:16505478).

UniProt: Q86YW5