ICAM5 ELISA Kit

Catalog No. ABIN5510695

This Colorimetric ELISA kit is designed for the quantitative measurement of Human ICAM5.

Quick Overview for ICAM5 ELISA Kit (ABIN5510695)

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Binding Specificity: AA 28-570

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Product Details ICAM5 ELISA Kit

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human ICAM5

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO
Immunogen sequence: A28-E570

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for ICAM5

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Alternative Name: ICAM5

Background:

Protein Function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).

Background: Intercellular adhesion molecule 5 is a protein that in humans is encoded by the ICAM5 gene. The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

Synonyms: Intercellular adhesion molecule 5,ICAM-5,Telencephalin,ICAM5,TLCN, TLN,

Full Gene Name: Intercellular adhesion molecule 5

Cellular Localisation: Membrane, Single-pass type I membrane protein.

UniProt: Q9UMF0

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location