BCAM ELISA Kit

Catalog No. ABIN5510708

This Human BCAM ELISA Kit is a Colorimetric ELISA Kit designed to quantify Human BCAM.

Quick Overview for BCAM ELISA Kit (ABIN5510708)

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Binding Specificity: AA 32-547

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Product Details BCAM ELISA Kit

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human BCAM

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO
Immunogen sequence: E32-A547

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for BCAM

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Alternative Name: BCAM

Background:

Protein Function: Laminin alpha-5 receptor. May mediate intracellular signaling. .

Background: Basal cell adhesion molecule is a protein that in humans is encoded by the BCAM gene. The BCAM gene encodes a glycoprotein expressed on cell surfaces. It is a member of the immunoglobulin superfamily of receptors and cell adhesion molecules. When expressed on erythrocytes, BCAM constitutes the Lutheran (Lu) and Auberger (Au) blood group antigens. And this protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: Basal cell adhesion molecule,Auberger B antigen,B-CAM cell surface glycoprotein,F8/G253 antigen,Lutheran antigen,Lutheran blood group glycoprotein,CD239,BCAM,LU, MSK19,

Full Gene Name: Basal cell adhesion molecule

Cellular Localisation: Membrane, Single-pass type I membrane protein.

UniProt: P50895