Syndecan 1 ELISA Kit

Catalog No. ABIN5510712

Mouse Syndecan 1 ELISA Kit Colorimetric assay for quantification of Mouse Syndecan 1.

Quick Overview for Syndecan 1 ELISA Kit (ABIN5510712)

Target: Syndecan 1 (SDC1)

Binding Specificity: AA 18-252

Reactivity: Mouse

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Product Details Syndecan 1 ELISA Kit

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Syndecan-1/SDC1

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO
Immunogen sequence: Q18-E252

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for Syndecan 1

Target: Syndecan 1 (SDC1)

Alternative Name: Sdc1

Background:

Protein Function: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. .

Background: Syndecan 1, also known as SYND1 or CD138, is a protein which in humans is encoded by the SDC1 gene. The protein encoded by this gene is a transmembrane(type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. This gene is mapped to 2p24.1. The syndecans mediate cell binding, cell signaling, cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan 1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. What’s more, Syndecan-1 is also a sponge for growth factors, with binding largely via heparan sulfate chains.

Synonyms: Syndecan-1,SYND1,CD138,Sdc1,Synd-1, Synd1,

Full Gene Name: Syndecan-1

Cellular Localisation: Membrane, Single-pass type I membrane protein . Secreted . Secreted, exosome . Shedding of the ectodomain produces a soluble form..

UniProt: P18828

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism