GDF2 ELISA Kit
Quick Overview for GDF2 ELISA Kit (ABIN5510718)
Target
See all GDF2 ELISA KitsBinding Specificity
Reactivity
Detection Method
Method Type
Application
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Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human BMP-9
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Analytical Method
- Quantitative
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Specificity
- Expression system for standard: CHO, Immunogen sequence: S320-R429
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Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Growth Differentiation Factor 2 (GDF2) ELISA Kit
GDF2 Reactivity: Human Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Growth Differentiation Factor 2 (GDF2) ELISA KitGDF2 Reactivity: Mouse Colorimetric Sandwich ELISA 78.12 pg/mL - 5000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Growth Differentiation Factor 2 (GDF2) ELISA KitGDF2 Reactivity: Rat Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Growth Differentiation Factor 2 (GDF2) ELISA KitGDF2 Reactivity: Rat AA 320-430 Colorimetric Sandwich ELISA
Growth Differentiation Factor 2 (GDF2) ELISA KitGDF2 Reactivity: Mouse AA 319-428 Colorimetric Sandwich ELISA
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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Expiry Date
- 12 months
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- GDF2 (Growth Differentiation Factor 2 (GDF2))
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Alternative Name
- GDF2
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Background
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Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.
Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.
Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, GDF2, BMP9,
Full Gene Name: growth differentiation factor 2
Cellular Localisation: Secreted -
UniProt
- Q9UK05
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Pathways
- Transition Metal Ion Homeostasis
Target See all GDF2 ELISA Kits
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