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GDF2 ELISA Kit

Mouse GDF2 ELISA Kit Colorimetric assay for quantification of Mouse GDF2.
Catalog No. ABIN5510748

Quick Overview for GDF2 ELISA Kit (ABIN5510748)

Target

See all GDF2 ELISA Kits
GDF2 (Growth Differentiation Factor 2 (GDF2))

Binding Specificity

AA 319-428

Reactivity

  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Mouse

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Application

ELISA
  • Purpose

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse BMP-9

    Brand

    PicoKine™

    Analytical Method

    Quantitative

    Specificity

    Expression system for standard: CHO, Immunogen sequence: S319-R428

    Cross-Reactivity (Details)

    There is no detectable cross-reactivity with other relevant proteins.
  • Plate

    Pre-coated

    Restrictions

    For Research Use only
  • Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    Expiry Date

    12 months
  • Target See all GDF2 ELISA Kits

    GDF2 (Growth Differentiation Factor 2 (GDF2))

    Alternative Name

    Gdf2

    Background

    Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

    Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.

    Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, Gdf2, Bmp9,

    Full Gene Name: growth differentiation factor 2

    Cellular Localisation: Secreted.

    UniProt

    Q9WV56

    Pathways

    Transition Metal Ion Homeostasis
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