ModDetect® Phosphorothioate Biotinylated Panel

Catalog No. ABIN7675638

Supplier Product No.: kna-101

Quick Overview for ModDetect® Phosphorothioate Biotinylated Panel (ABIN7675638)

Target: DNA (Deoxyribonucleic Acid (DNA))

Product Details

Binding Specificity: Phosphorothioate

Clonality: Monoclonal

Conjugate: Biotin

Supplier Product No.: kna-101

Supplier: Rockland

Purpose: ModDetect® Phosphorothioate Biotin Panel

Brand: ModDetect®

Components: The set includes five ModDetect® phosphorothioate biotin labeled detection reagents [clone PS03 (200-306-MU9S), clone PS04 (200-306-MV0S), clone PS05 (200-306-MV1S), clone PS07 (200-306-MW0S), and clone PS09 (200-306-MW3S)], curated by binding characteristics, and three reporter molecules labeled with peroxidase (ABIN964537), 488 λ fluorophore (S000-41) and 649 λ fluorophore (S000-43). The different binding characteristics create opportunities to generate highly optimized immunoassays independent of oligonucleotide sequence, as opposed to spending significant efforts to optimize assays to underperforming reagents. Designed for use in various immunoassays, such as ELISA, IF, and IHC.
NOTE: Panel detection reagents components are provided in a 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride buffer, pH 7.2. This buffer contains 0.01 % Sodium Azide as a preservative and 10 mg/mL carrier protein as a stabilizing reagent.

Product Specific Information:

The ModDetect™ Phosphorothioate (PS) Biotinylated Panel is designed for immunoassay workflows requiring biotin-mediated capture or detection. It provides modification-specific recognition of PS linkages while enabling flexible assay configurations. Biotinylation supports use in sandwich ELISAs, plate-based capture assays, and streptavidin-driven formats. This panel enables sequence-independent detection of PS-modified oligonucleotides across multiple therapeutic modalities. It is well suited for quantitative and comparative bioanalytical applications in research and preclinical studies.

Application Details

Application Notes: Designed for use in various immunoassays, such as ELISA, IF, and IHC and establishment of said assays

Restrictions: For Research Use only

Handling

Format: Lyophilized or Liquid

Buffer: Panel detection reagents components are provided in a 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride buffer, pH 7.2. This buffer contains 0.01 % Sodium Azide as a preservative and 10 mg/mL carrier protein as a stabilizing reagent.

Handling Advice: Avoid cycles of freezing and thawing. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.

Storage: 4 °C,-20 °C

Storage Comment: Store five phosphorothioate vials at -20°C or below prior to opening. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing. Store three reporter molecule vials at 4°C or -20°C prior to restoration. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details

Target: DNA (Deoxyribonucleic Acid (DNA))

Alternative Name: DNA

Target Type: Chemical

Background: Phosphorothioate, PS, ASO, anti-sense oligonucleotide