Prostate Specific Antigen ELISA Kit

Catalog No. ABIN996897

This Human Prostate Specific Antigen ELISA Kit is a Colorimetric ELISA Kit designed to quantify Human Prostate Specific Antigen.

Quick Overview for Prostate Specific Antigen ELISA Kit (ABIN996897)

Target: Prostate Specific Antigen (PSA)

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 0-60 ng/mL

Application: ELISA

Sample Type: Serum

Product Details Prostate Specific Antigen ELISA Kit

Minimum Detection Limit: 0 ng/mL

Purpose: The PSA Enzyme Immunoassay test kit is intended for the quantitative determination of PSA in human serum.

Analytical Method: Quantitative

Specificity: 98.7 %

Sensitivity: 0.5 ng/mL

Application Details

Sample Volume: 25 μL

Assay Time: 1 h

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C

Expiry Date: 12 months

Target Details for Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Alternative Name: PSA

Background: Human prostate-specific antigen (PSA) is a serine protease, a sigle chain glycoprotein with a molecular weight of approximately 34,000 daltons containing 7% carbohydrate by weight. PSA is immunologically specific for prostatic tissue, it is present in normal, benign hyperplastic, and malllignant prostatic tissue, in metastatic prostatic carcinoma, and also in prostatic fluid and seminal plasma. PSA is not present in any other normal tissue obtained from men, nor is it produced by cancers of the breast, lung, colon, rectum, stomach, pancreas or thyroid. Besides, it is functionally and immunologically different from prostatic acid phosphatase (PAP). Elevated serum PSA concentrations have been reported in patients with prostate cancer, benign prostatic hypertrophy, or inflammatory conditions of other adjacent genitourinary tissues, but not in apparently healthy men, men with non-prostatic carcinoma, apparently healthy women, or women with cancer. Reports have suggested that serum PSA is one of the most useful tumor markers in oncology. It may serves as an accurate marker for assessing response to treatment in patients with prostatic cancer. Therefore, measurement of serum PSA concentrations can be an important tool in monitoring patients with prostatic cancer and in determining the potential and actual effectiveness of surgery or other therapies. Recent studies also indicate that PSA measurements can enhancce early prostate cancer detection when combined with digital rectal examination (DRE).

Pathways: Complement System