Helicobacter Pylori Antigen ELISA Kit

Catalog No. ABIN997009

Helicobacter pylori ELISA Kit Colorimetric assay for quantification of Helicobacter pylori .

Quick Overview for Helicobacter Pylori Antigen ELISA Kit (ABIN997009)

Target: Helicobacter Pylori Antigen

Reactivity: Helicobacter pylori

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 0-100 ng/mL

Application: ELISA

Product Details

Minimum Detection Limit: 0 ng/mL

Purpose: ELISA, Helicobacter pylori Antigen is a quantitative assay for the detection of H. pylori antigens in human stool specimen.

Analytical Method: Quantitative

Sensitivity: 0.5 ng/mL

Application Details

Assay Time: 1 - 2 h

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C

Expiry Date: 12-18 months

Target Details

Target: Helicobacter Pylori Antigen

Background: Helicobacter pylori is a spiral bacterium cultured from human gastric mucosa by Marshall in 1982. Studies have indicated that the presence of H. pylori is associated with a variety of gastrointestinal diseases including gastritis, duodenal and gastric ulcer, non-ulcer dyspepsia, gastric adenocarcinoma and lymphoma. The organism is present in 95-98% of patients with duodenal ulcer and 60-90% of patients with gastric ulcers. The studies have also demonstrated that removal of the organism by antimicrobial therapy is correlated with the resolution of symptoms and cure of diseases. Patients who present with clinical symptoms relating to the gastrointestinal tract can be diagnosed for H. pylori infection by two methods: 1) Invasive techniques include biopsy followed by culture or histological examination of biopsy specimen or direct detection of urease activity. The cost and discomfort to the patients are very high and biopsy samples are subject to errors related to sampling and interference of contaminated bacteria. 2) Non-invasive techniques include urea breath tests (UBT) and serological methods. The UBT requires a high density and active bacteria and should not be performed until 4 weeks after therapy to allow resisdual bacteria to increase to the detection level. The main limitation of serology test is the inability to distinguish current and past infections.