KLHL12 Proteins

(Kelch-Like 12 (Drosophila) (KLHL12))

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). As part of the BCR(KLHL12) complex, also acts as a negative regulator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3 (By similarity).

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KLHL12 Protein (AA 1-568) (His tag)

custom-made KLHL12 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Klhl12 Protein, UniprotID Q8BZM0

3 images

Catalog No. ABIN7564476

Details

KLHL12 Protein (AA 1-568) (His tag)

custom-made KLHL12 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant KLHL12 Protein, UniprotID Q53G59

3 images

Catalog No. ABIN7554291

Details

KLHL12 Protein (AA 1-568) (GST tag)

KLHL12 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Kelch-Like 12 (Drosophila) (KLHL12) (AA 1-568) protein (GST tag) (ABIN1308796)

1 image

Catalog No. ABIN1308796

Details

KLHL12 Protein (AA 1-568) (His tag)

KLHL12 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

Western Blotting (WB) image for Kelch-Like 12 (Drosophila) (KLHL12) (AA 1-568) protein (His tag) (ABIN7123668)

1 image

Catalog No. ABIN7123668

Details

KLHL12 Protein (AA 1-568) (Strep Tag)

custom-made KLHL12 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3136331

Details

KLHL12 Protein (AA 1-568) (Strep Tag)

custom-made KLHL12 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3093355