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LAG3 Proteins

(Lymphocyte-Activation Gene 3 (LAG3))
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008].

38 results

LAG3 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN6573855
 
LAG3 Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Catalog No. ABIN7575644
 
LAG3 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN4371557
 
LAG3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
Catalog No. ABIN7405499
 
LAG3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Catalog No. ABIN7405442
 
LAG3 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7417309
 
LAG3 Origin: Human Host: Wheat germ Recombinant AP
Catalog No. ABIN1330273
 
LAG3 Origin: Rat Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN2870839
 
LAG3 Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2870833
 
LAG3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713512
 
LAG3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7121268
 
MALS verified LAG3 Origin: Dog Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7121274
 
MALS verified LAG3 Origin: Mouse Host: HEK-293 Cells Recombinant 90 %
Catalog No. ABIN7482579
 
LAG3 Origin: Human Host: Human Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. WB, SDS, ELISA, MS
Catalog No. ABIN7314158
 
LAG3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7199111
 
LAG3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7199107
 
MALS verified LAG3 Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7199037
 
LAG3 Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1632445
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Flow Cytometry (FACS)
    • Mass Spectrometry (MS)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Cynomolgus
    • Rat
    • Dog
    • Monkey
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • HEK-293 Cells
    • Human Cells
    • Escherichia coli (E. coli)
    • Wheat germ
    • CHO Cells
    • Mammalian Cells
    • Yeast
  • Binding Specificity
    • AA 23-450
    • AA 24-442
    • AA 23-245
    • AA 23-434
    • AA 23-442
    • AA 1-360
    • AA 18-449
    • AA 209-451
    • AA 23-222
    • AA 244-487
    • AA 274-504
  • Conjugate
    • His tag
    • Fc Tag
    • His-Avi Tag,Biotin
    • Un-conjugated
    • DYKDDDDK-His Tag
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,Biotin
    • GST tag
    • His-IF2DI Tag
    • mFc Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Grade
    • MALS verified
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • CUSABIO
    • Cohesion Biosciences
    • OriGene

Latest Publications for our LAG3 Proteins

Yuan, Long, Wei, Wang, Zhu, Han, Jiang, Lan, Gai: "Peptide-based PET tracer targeting LAG-3 for evaluating the efficacy of immunotherapy in melanoma." in: Journal for immunotherapy of cancer, Vol. 12, Issue 7, (2024) (PubMed).

Yu, Huang, Chen, Liu, Wu, Pu, Wang, Kang, Zhou: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).

Xu, Qin, Hao, He, Chen, Zhang, Peng, Wen, Chen, Qiu, Li: "A signal-decreased electrochemical immunosensor for the sensitive detection of LAG-3 protein based on a hollow nanobox-MOFs/AuPt alloy." in: Biosensors & bioelectronics, Vol. 113, pp. 148-156, (2018) (PubMed).

Brignone, Grygar, Marcu, Schäkel, Triebel: "A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 4202-11, (2007) (PubMed).

Triebel, Hacene, Pichon: "A soluble lymphocyte activation gene-3 (sLAG-3) protein as a prognostic factor in human breast cancer expressing estrogen or progesterone receptors." in: Cancer letters, Vol. 235, Issue 1, pp. 147-53, (2006) (PubMed).

Buisson, Triebel: "LAG-3 (CD223) reduces macrophage and dendritic cell differentiation from monocyte precursors." in: Immunology, Vol. 114, Issue 3, pp. 369-74, (2005) (PubMed).

Cappello, Triebel, Iezzi, Caorsi, Quaglino, Lollini, Amici, Di Carlo, Musiani, Giovarelli, Forni: "LAG-3 enables DNA vaccination to persistently prevent mammary carcinogenesis in HER-2/neu transgenic BALB/c mice." in: Cancer research, Vol. 63, Issue 10, pp. 2518-25, (2003) (PubMed).

Andreae, Piras, Burdin, Triebel: "Maturation and activation of dendritic cells induced by lymphocyte activation gene-3 (CD223)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 8, pp. 3874-80, (2002) (PubMed).

Huard, Prigent, Pagès, Bruniquel, Triebel: "T cell major histocompatibility complex class II molecules down-regulate CD4+ T cell clone responses following LAG-3 binding." in: European journal of immunology, Vol. 26, Issue 5, pp. 1180-6, (1996) (PubMed).

Huard, Prigent, Tournier, Bruniquel, Triebel: "CD4/major histocompatibility complex class II interaction analyzed with CD4- and lymphocyte activation gene-3 (LAG-3)-Ig fusion proteins." in: European journal of immunology, Vol. 25, Issue 9, pp. 2718-21, (1995) (PubMed).

Aliases for LAG3 Proteins

lymphocyte activating 3 (LAG3) Proteins
lymphocyte-activation gene 3 (Lag3) Proteins
lymphocyte activating 3 (Lag3) Proteins
CD223 Proteins
LAG-3 Proteins
Ly66 Proteins
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