EDG-6
S1PR4
WB, PC
Whole Cell Lysate
Catalog No. ABIN924992
$553.85
Plus shipping costs $50.00
100 μL
Shipping to:
United States
Delivery in 11 to 17 Business Days
Quick Overview for EDG-6 (ABIN924992)
Target
S1PR4
(Sphingosine-1-Phosphate Receptor 4 (S1PR4))
Application
Western Blotting (WB), Positive Control (PC)
Lysate Fraction
Whole Cell Lysate
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Application Notes
- For use as a positive control with EDG-6 polyclonal antibody ABIN187788 for Western blot analysis. Use 10-20 µl of EDG-6 cell lysate per lane as a control when using EDG-6 antibody.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Provided in 10% glycerol, 063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue and 5% 2-mercaptoethanol.
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Storage
- -20 °C
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- S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))
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Alternative Name
- EDG-6
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Background
- EDG-6 Trnasfected Cell Positive Control Lysate. EDG-6 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-6 is a sphingosine-1- phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG-6 is expressed in lymphoid and hematopoietic tissue and in the lungs.
Target
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