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MARCH4 Products

(Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))

Categories

MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010].

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Featured MARCH4 Categories

MARCH4 Antibodies

High quality antibodies with extensive validation data.

MARCH4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MARCH4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN657255
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN566137
Quantity 50 μL
Datasheet Datasheet
Reactivity Horse, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6740812
Quantity 100 μL
Datasheet Datasheet

Recommended MARCH4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310367
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
Cat. No. ABIN3124246
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN3118772
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MARCH4 products

Bartee, Mansouri, Hovey Nerenberg, Gouveia, Früh: "Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins." in: Journal of virology, Vol. 78, Issue 3, pp. 1109-20, (2004) (PubMed).

Synonyms and alternative names related to MARCH4

membrane associated ring-CH-type finger 4 (MARCH4), membrane associated ring-CH-type finger 4 (March4), membrane-associated ring finger (C3HC4) 4 (March4), membrane-associated ring finger (C3HC4) 4 (march4), BC056494, MARCH-IV, MARCH4, mKIAA1399, RNF174, si:ch211-239d11.2

Protein level used designations for MARCH4

  • E3 ubiquitin-protein ligase MARCH4
  • RING finger protein 174
  • membrane-associated RING finger protein 4
  • membrane-associated RING-CH protein IV
  • membrane-associated ring finger (C3HC4) 4
  • MARCH-IV
  • E3 ubiquitin-protein ligase MARCH4-like
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