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MARCH1 Products

(Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))

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MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]\; Thibodeau et al., 2008 [PubMed 18389477]\; De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010].

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Featured MARCH1 Categories

MARCH1 Antibodies

High quality antibodies with extensive validation data.

MARCH1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MARCH1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IF, ICC
Validations
  • (2)
Cat. No. ABIN6263124
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC
Validations
  • (1)
  • (2)
Cat. No. ABIN7301464
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN565806
Quantity 50 μL
Datasheet Datasheet

Recommended MARCH1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310354
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310352
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
Cat. No. ABIN3123578
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MARCH1 products

Bai, Mo, Wang, Chen, Zhang, Guo, Sun: "Intervention of Gastrodin in Type 2 Diabetes Mellitus and Its Mechanism." in: Frontiers in pharmacology, Vol. 12, pp. 710722, (2021) (PubMed).

Matsuki, Ohmura-Hoshino, Goto, Aoki, Mito-Yoshida, Uematsu, Hasegawa, Koseki, Ohara, Nakayama, Toyooka, Matsuoka, Hotta, Yamamoto, Ishido: "Novel regulation of MHC class II function in B cells." in: The EMBO journal, Vol. 26, Issue 3, pp. 846-54, (2007) (PubMed).

Synonyms and alternative names related to MARCH1

membrane associated ring-CH-type finger 1 (MARCH1), membrane-associated ring finger (C3HC4) 1 (March1), membrane associated ring-CH-type finger 1 (March1), 2900024D24Rik, BB085186, DKFZp459K1250, MARCH-I, MARCH1, RGD1305148, RNF171

Protein level used designations for MARCH1

  • E3 ubiquitin-protein ligase MARCH1
  • RING finger protein 171
  • membrane-associated RING finger protein 1
  • membrane-associated RING-CH protein I
  • MARCH-I
  • membrane-associated ring finger (C3HC4) 1
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