MARK1 Products
(MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))
Categories
Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3) (By similarity).
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Featured MARK1 Categories
MARK1 Antibodies
High quality antibodies with extensive validation data.
MARK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
MARK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MARK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7169067
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN391219
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
- (1)
Cat. No.
ABIN391220
Quantity
400 μL
Datasheet
Datasheet
Recommended MARK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1157247
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1157248
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1157249
Quantity
96 tests
Datasheet
Datasheet
Recommended MARK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5569742
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5570637
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3093697
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our MARK1 products
: "Role of partitioning-defective 1/microtubule affinity-regulating kinases in the morphogenetic activity of Helicobacter pylori CagA." in: The Journal of biological chemistry, Vol. 284, Issue 34, pp. 23024-36, (2009) (PubMed).: "Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2414-25, (2008) (PubMed).
: "Structural variations in the catalytic and ubiquitin-associated domains of microtubule-associated protein/microtubule affinity regulating kinase (MARK) 1 and MARK2." in: The Journal of biological chemistry, Vol. 281, Issue 37, pp. 27586-99, (2006) (PubMed).
Synonyms and alternative names related to MARK1
MAP/microtubule affinity-regulating kinase 1 S homeolog (mark1.S), microtubule affinity regulating kinase 1 (MARK1), MAP/microtubule affinity-regulating kinase 1 (mark1), microtubule affinity regulating kinase 1 (mark1), MAP/microtubule affinity regulating kinase 1 (Mark1), microtubule affinity regulating kinase 1 (Mark1), AW491150, B930025N23Rik, Emk3, MARK, MARK1, MGC80341, mKIAA1477, mPar-1c, Par-1c, Par1cProtein level used designations for MARK1
- MAP/microtubule affinity-regulating kinase 1
- chemokine CCL-CUc
- serine/threonine-protein kinase MARK1
- serine/threonine-protein kinase MARK1-like
- ELKL motif serine-threonine protein kinase 3
- ELKL motif serine/threonine-protein kinase 3
- PAR1 homolog c
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