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MARK1 Products

(MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))
Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3) (By similarity).

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Featured MARK1 Categories

MARK1 Antibodies

High quality antibodies with extensive validation data.

MARK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MARK1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MARK1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7169067
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat, Zebrafish (Danio rerio)
Application IC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN2706506
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN3031687
Quantity 0.4 mL
Datasheet Datasheet

Recommended MARK1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1157248
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1157247
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1157249
Quantity 96 tests
Datasheet Datasheet

Recommended MARK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (2)
Cat. No. ABIN5569742
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (2)
Cat. No. ABIN5570637
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093697
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MARK1 products

Lu, Murata-Kamiya, Saito, Hatakeyama: "Role of partitioning-defective 1/microtubule affinity-regulating kinases in the morphogenetic activity of Helicobacter pylori CagA." in: The Journal of biological chemistry, Vol. 284, Issue 34, pp. 23024-36, (2009) (PubMed).

Hezel, Gurumurthy, Granot, Swisa, Chu, Bailey, Dor, Bardeesy, Depinho: "Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2414-25, (2008) (PubMed).

Marx, Nugoor, Müller, Panneerselvam, Timm, Bilang, Mylonas, Svergun, Mandelkow, Mandelkow: "Structural variations in the catalytic and ubiquitin-associated domains of microtubule-associated protein/microtubule affinity regulating kinase (MARK) 1 and MARK2." in: The Journal of biological chemistry, Vol. 281, Issue 37, pp. 27586-99, (2006) (PubMed).

Synonyms and alternative names related to MARK1

MAP/microtubule affinity-regulating kinase 1 S homeolog (mark1.S), microtubule affinity regulating kinase 1 (MARK1), MAP/microtubule affinity-regulating kinase 1 (mark1), microtubule affinity regulating kinase 1 (mark1), MAP/microtubule affinity regulating kinase 1 (Mark1), microtubule affinity regulating kinase 1 (Mark1), AW491150, B930025N23Rik, Emk3, MARK, MARK1, MGC80341, mKIAA1477, mPar-1c, Par-1c, Par1c

Protein level used designations for MARK1

  • MAP/microtubule affinity-regulating kinase 1
  • chemokine CCL-CUc
  • serine/threonine-protein kinase MARK1
  • serine/threonine-protein kinase MARK1-like
  • ELKL motif serine-threonine protein kinase 3
  • ELKL motif serine/threonine-protein kinase 3
  • PAR1 homolog c
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