Browse our anti-PPARG (PPARG) Antibodies

Mouse (Murine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

1. For the first time, we report here the importance of GPER (show GPER Antibodies)-PPARalpha (show PPARA Antibodies) and -PPARgamma 'neopartnership' in maintenance of Leydig cell morpho-functional status.

2. Data show that a peroxisome proliferator activated receptor gamma (PPARgamma)-dependent adipogenic response regulates muscle fat infiltration during regeneration.

3. the intracellular domain of Lrp1 (show LRP1 Antibodies) interacts with the nuclear receptor Ppargamma, a central regulator of lipid and glucose metabolism, acting as its transcriptional co-activator in endothelial cells.

4. High fat diet-induced obesity exacerbates hematopoiesis deficiency and cytopenia caused by 5-fluorouracil via peroxisome proliferator-activated receptor gamma.

5. findings suggest that MCAM (show MCAM Antibodies) is a gene upregulated and involved in maintaining PPARgamma induction in the late but not in the early stages of 3T3-L1 fibroblasts adipogenesis.

6. This study shows that prolonged exposure to high-fat diets in adulthood is associated with a gradually increasing DNA methylation (show HELLS Antibodies) level at the Leptin (show LEP Antibodies) and Pparg2 promoters in a depot-specific manner.

7. Results suggest that hypothalamic peroxisome proliferator-activated receptor-gamma plays a vital role in ghrelin (show GHRL Antibodies) production and food intake in mice.

8. Data suggest that expression of microRNA-128-3p is down-regulated during adipogenesis; an abundance of microRNA-128-3p appears to down-regulate adipogenesis and up-regulate lipolysis in adipocytes by targeting expression of Pparg (peroxisome proliferator-activated receptor gamma) and Sertad2 (SERTA domain-containing protein-2 (show SERTAD2 Antibodies)).

9. The present study suggests for the first time that increased PPAR (show PPARA Antibodies)-gmma expression by high fat diet is responsible for cardiac dysfunction via upregulation of mitochondrial enzymes HMGCS2 (show HMGCS2 Antibodies), BDH1 (show BDH1 Antibodies) and PDK4 (show PDK4 Antibodies).

10. Data suggests that exposure to vitamin D deficiency during perinatal period directly affects expression of genes involved in development of adipose tissue in non-obese offspring; expression levels of Pparg (peroxisome proliferator activated receptor gamma) and Vdr (vitamin D receptor) are up-regulated in adipose tissue of male offspring.

Human Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

1. Studies indicate that peroxisome proliferator activated receptor gamma (PPARgamma) expression is found in different regions of the kidney and, upon activation, can redirect metabolism [Review].

2. These results demonstrate that betaine acts through ERK1/2-PPARgamma signalling pathway to regulate lipid metabolism in adipogenic-differentiated skeletal muscle cells, which could provide some useful information for controlling muscle lipid accumulation by manipulating ERK1/2 and PPARgamma signalling pathway.

3. ALDH1A3 (show ALDH1A3 Antibodies) suppression could be one of PPARG tumor suppressive function. This study provides a better understanding of the role of PPARG in lung cancer.

4. Regulation of transmembrane-4-L-six-family-1 (TM4SF1 (show TM4SF1 Antibodies)) on bladder cancer cell could be induced by peroxisome proliferator-activated receptor gamma (PPARgamma)-sirtuin 1 (SIRT1 (show SIRT1 Antibodies)) feedback loop.

5. The lack of PPARγ in recurrent miscarriage decidual macrophages seems to be associated with a specific inflammatory response against the fetus.

6. EDF1 (show EDF1 Antibodies) is required for VEGF (show VEGFA Antibodies)-induced activation of the transcriptional activity of PPARgamma in HUVEC cells.

7. Studied peroxisome proliferator-activated receptor-gamma gene (PPARgamma) single nucleotide polymorphisms (SNPs); found the SNPs to be associated with the occurrence or progression of sepsis.

8. This study suggests that T2D patients with different genotypes at CD36 (show CD36 Antibodies), NOS3 (show NANOS3 Antibodies) and PPARG respond differentially to intervention of omega-3 supplements in blood lipid profiles.

9. ITLN1 (show ITLN1 Antibodies), PPARg AND TNFa (show TNF Antibodies) GENE EXPRESSION IN VISCERAL ADIPOSE TISSUE.

10. Gene expressions of YKL-40 (show CHI3L1 Antibodies) and CD36 (show CD36 Antibodies) were significantly higher in patients with T2DM (>5 yr) with hypertension compared to healthy controls (P=0.006). In addition, a significant increase in serum levels of sCD36, PPAR-gamma and YKL-40 (show CHI3L1 Antibodies) was observed in patients with T2DM (>5 yr) with hypertension compared to healthy controls

Pig (Porcine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

1. Our results provide novel insights into regulation of PPAR (show PPARA Antibodies) expression in ovarian follicles. We observed that FSH (show BRD2 Antibodies) increased mRNA and protein expression of all PPARs isoforms, while LH only increased PPAR alpha (show PPARA Antibodies) and gamma. Steroids like progesterone and estradiol increased expression of PPAR alpha (show PPARA Antibodies) and gamma without affecting the beta isoform, while testosterone had no effect on all PPARs expression.

2. The results of the present study suggested that PPARG may mediate porcine placental angiogenesis, by interfering with hypoxia inducible factor, vascular endothelial growth factor (show VEGF Antibodies) and angiopoietinmediated signaling.

3. The results suggest the higher expression of miR (show MYLIP Antibodies)-130a, which targeting peroxisome proliferator-activated receptor gamma, may be the reason for less fat deposition in intramuscular adipose tissue than subcutaneous adipose tissue.

4. The immunoprecipitation results also showed that high AA concentrations significantly increased the interaction of mTOR (show FRAP1 Antibodies) and PPARg. In summary, PPARg plays an important role in the regulation of IGF-1 (show IGF1 Antibodies) secretion and gene expression in response to dietary protein.

5. The regulatory role of microRNA miR (show MYLIP Antibodies)-27b-3p on peroxisome proliferator-activated receptor-gamma (PPARgamma) was confirmed by their inversed expression patterns in oocytes: [miR (show MYLIP Antibodies)-27b-3p]

6. an Enhancer box and a binding site for a cooperative co-activator of MyoD (show MYOD1 Antibodies) are present in the promoter region of porcine PPARgamma.

7. The data suggest that there is local cooperation between resistin (show RETN Antibodies) and PPARgamma expression in the porcine ovary. Resistin (show RETN Antibodies) significantly increased the expression of PPARgamma, whereas PPARgamma decreased resistin (show RETN Antibodies) expression; thus, PPARgamma is a new key regulator of resistin (show RETN Antibodies) expression and function.

8. Therefore, this study demonstrated that the different regulatory adipogenic roles of MSTN (show MSTN Antibodies) in ADSCs and MSCs act by differentially regulating PPARgamma and MyoD (show MYOD1 Antibodies) expression.

9. PGRN (show GRN Antibodies) inhibits adipogenesis in porcine preadipocytes partially through ERK (show MAPK1 Antibodies) activation mediated PPARgamma phosphorylation.

10. Resveratrol activated sirtuin 1 (Sirt1 (show SIRT1 Antibodies)) gene expression and increased adipose triglyceride lipase (ATGL (show PNPLA2 Antibodies)) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 (show SIRT1 Antibodies) regulation pattern for PPARgamma to that of ATGL (show PNPLA2 Antibodies) in adipocytes.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

1. Three novel SNPs of the bovine PPARgamma gene were identified in 514 individuals from six Chinese cattle breeds: SNP1 (AC_000179.1 g.57386668 C > G) in intron 2 and SNP2 (AC_000179.1 g.57431964 C > T) and SNP3 (AC_000179.1 g.57431994 T > C) in exon 7.

2. These results indicated that docosahexaenoic acid may attenuate lipopolysaccharide-stimulated inflammatory response in bovine mammary epithelial cells by suppressing NF-kappaB (show NFKB1 Antibodies) activation through a mechanism partly dependent on PPARgamma activation.

3. PPARgamma is a positive regulator of milk fat synthesis in dairy cow mammary epithelial cells.

4. An Asp7Gly substitution in PPARG is associated with adiposity.

5. upregulation of PPARgamma was observed in the backfat tissue of Lilu cattle with increasing age

6. Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta (show CEBPB Antibodies) and PPAR-gamma gene expression in differentiated myoblasts and an increase in GPR43 (show FFAR2 Antibodies) gene expression in adipocytes.

7. A potential association of an single nucleotide polymorphism (72472 GT in exon7) of the bovine PPAR-gamma gene with carcass and meat quality traits, was evaluated.

8. study demonstrates the co-expression of DLX3 (show DLX3 Antibodies), PPARG and SP1 (show SP1 Antibodies) in trophoblast binucleated cell(BNC)nuclei; this suggests a possible role of these transcription factors through BNC specific genes at the time of pre-placental differentiation

9. Single nucleotide polymorphisms in coding region of the PPARgamma gene, were examined.

10. oxidative stress attenuates PPAR gamma expression and activity in vascular endothelial cells

Rhesus Monkey Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

1. study found PPAR-gamma expression was prominent in the subthalamic nucleus, oculomotor nucleus, ventral tegmental nucleus, and to a lesser extent, in the putamen; 3 or 12 months after MPTP (show PTPN2 Antibodies), only the lesioned putamen had increased PPAR-gamma

2. Aleglitazar, a dual PPARalpha (show PPARA Antibodies)/gamma agonist, has beneficial effects on both lipid and glucose parameters in a primate model of the metabolic syndrome.

Rabbit Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

1. the present study demonstrated that RS protects primary myocardial cells against OGD (show FGFR1 Antibodies)/R injury by regulating PPARgamma and UCP2 (show UCP2 Antibodies). RS may be a promising therapeutic agent for treatment of myocardial ischemia/reperfusion injury.

2. siRNA targeting PPARgamma gene can inhibit adipogenic differentiation of BMSCs and prevent steroid-induced osteonecrosis in rabbit.

3. vitamin E supplementation affords protection by decreasing MMP-1 (show MMP1 Antibodies) and increasing PPARg, GSTa (show GSTa2 Antibodies), and ABCA1 (show ABCA1 Antibodies) levels in aortae of rabbits fed a cholesterol-rich diet

4. Telmisartan improves microvascular dysfunction during myocardial ischemia/reperfusion injury via the PPARgamma pathway.

5. PPARgamma plays a luteotropic role in pseudopregnant rabbits, through PTGS2 (show PTGS2 Antibodies) down-regulation and 3beta-HSD (show HAL Antibodies) up-regulation, with a consequent PGF2alpha decrease and progesterone increase.

6. In an animal model of atherosclerosis, the expression of PPAR-gamma is upregulated following atorvastatin administration.

7. Tongxinluo can inhibit the expression of MMP-3 (show MMP3 Antibodies) and 9 and increase the expression of PPARgamma in atherosclerotic rabbits.

8. Niacin Reduces serum level and adipose mRNA expression of leptin (show LEP Antibodies) and up-regulates PPARgamma and CD36 (show CD36 Antibodies) mRNA expression in hypercholesterolemic rabbits.

9. Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase (show PIK3CA Antibodies), Akt (show AKT1 Antibodies), and eNOS (show NOS3 Antibodies) pathway in a rabbit model of myocardial infarction.