NEDD4-2 Proteins

(E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].

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5 results

NEDD4-2 Protein (AA 1-1004) (His tag)

custom-made NEDD4L Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Nedd4l Protein, UniprotID Q8CFI0

3 images

Catalog No. ABIN7564557

Details

NEDD4-2 Protein (AA 1-911) (GST tag)

NEDD4L Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 1-911) protein (GST tag) (ABIN1312322)

1 image

Catalog No. ABIN1312322

Details

NEDD4-2 Protein (His tag)

NEDD4L Origin: Human Host: Escherichia coli (E. coli) Recombinant ELISA, WB, SDS

Catalog No. ABIN7578417

Details

NEDD4-2 Protein (AA 1-1004) (Strep Tag)

custom-made NEDD4L Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3136435