Browse our anti-alpha Adducin (ADD1) Antibodies

Full name:: anti-Adducin 1 (Alpha) Antibodies (ADD1)

On www.antibodies-online.com are 189 Adducin 1 (Alpha) (ADD1) Antibodies from 25 different suppliers available. Additionally we are shipping alpha Adducin Proteins (6) and alpha Adducin Kits (1) and many more products for this protein. A total of 210 alpha Adducin products are currently listed.

Synonyms:: ADD1, add1-a, add2, adda, AI256389, alpha-adducin, bZ1H20.1, cb787, zgc:158352

list all antibodies	Gene Name	GeneID	UniProt
	ADD1	118	P35611
	ADD1	11518	Q9QYC0
	ADD1	24170	Q63028
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Most Popular Reactivities for anti-alpha Adducin (ADD1) Antibodies

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anti-Human alpha Adducin Antibodies:

anti-Mouse (Murine) alpha Adducin Antibodies:

anti-Rat (Rattus) alpha Adducin Antibodies:

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Top referenced anti-alpha Adducin Antibodies

Human Polyclonal alpha Adducin Primary Antibody for WB - ABIN2801956 : Joshi, Gilligan, Otto, McLaughlin, Bennett: Primary structure and domain organization of human alpha and beta adducin. in The Journal of cell biology 1991 (PubMed)
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More Antibodies against alpha Adducin Interaction Partners

Human Adducin 1 (Alpha) (ADD1) interaction partners

The ADD1 Gly460Trp gene polymorphism is significantly and independently associated with Essential Hypertension risk in a Caucasian population from Madeira Island.
ZNF322A (show ZNF322A Antibodies) overexpression transcriptionally dysregulates genes involved in cell growth and motility therefore contributes to lung tumorigenesis and poor prognosis
ADD1 rs4963 polymorphism showed an increased hypertension risk.
This indicates that ADD1 G460W polymorphism could be an important factor in the pathophysiology of tinnitus.
Study shows that ADD1-rs4963 conferred susceptibility to colorectal cancer (CRC (show CALR Antibodies)) suggesting an association between ADD1 and CRC (show CALR Antibodies) risk.
The T allele of ADD1 is associated with essential hypertension in Asians.
study of potential effects of interaction between DNA methylation (show HELLS Antibodies) of ADD1 promoter and ADD1 tagSNPs and environmental factors on essential hypertension (EH); results indicate ADD1 SNP rs4961 has a protective role in development of EH; interactions between alcohol consumption and DNA methylation (show HELLS Antibodies) of ADD1 gene promoter have a significant role in modifying EH susceptibility
There were significant differences between the control group and pediatric hypertensive group in terms of ACE (show ACE Antibodies) I/D (P<0.05) and AGT (show AGXT Antibodies) M235T (P<0.05) polymorphisms, but there were no differences in ADD Gly460Trp (P>0.05) polymorphism.
A significant association was found between ADD1 gene G614T polymorphism and essential hypertension in Chinese patients. Further studies need to be done to confirm these findings in a large sample.
When alpha-adducin complexes with sodium potassium ATPase (show DNAH8 Antibodies) in astrocytes, non-cell autonomous neurodegeneration is triggered.

Mouse (Murine) Adducin 1 (Alpha) (ADD1) interaction partners

Sez6l2 (show SEZ6L2 Antibodies) is one of the auxiliary subunits of the AMPA (show GRIA3 Antibodies) receptor and acts as a scaffolding protein to link GluR1 (show GRIA1 Antibodies) to ADD. Furthermore, Sez6l2 (show SEZ6L2 Antibodies) overexpression upregulates ADD phosphorylation, whereas siRNA-mediated downregulation of Sez612 prevents ADD phosphorylation, suggesting that Sez6l2 (show SEZ6L2 Antibodies) modulates AMPA (show GRIA3 Antibodies)-ADD signal transduction.
Reduction in ADD1 protein in NEK1 (show NEK1 Antibodies) mutant mice is associated with hyperphosphorylation of ADD1, thereby preventing the interaction with MYO10 (show MYO10 Antibodies) during meiotic spindle formation
adducin activity is not essential for actin ring assembly and periodicity but is necessary to control the diameter of both actin rings and axons and actin filament growth within rings.
Targeted deletion of Add1 reveals strain-dependent hyperkyphosis and megaesophagus in c57bl, 129s1 and B6 mice.
organization of a spectrin-like cytoskeleton is associated with keratinocyte differentiation, and cytoskeleton disruption is mediated by either PKCdelta (show PKCd Antibodies)(Thr505) phosphorylation associated with phosphorylated adducin or due to reduction of endogenous adducin
Reorganization of the unique cytoskeletal network defining a primary quiescent T cell is mediated thru the TCR-dependent modification & downregulation of alpha-adducin, resulting in a cytoskeletal shape compatible with T cell effector & memory functions.
Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin (show ADD3 Antibodies), compensated hemolytic anemia, and lethal hydrocephalus in mice

alpha Adducin (ADD1) Antigen Profile

Antigen Summary

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms\; however, not all variants have been fully described.

Alternative names and synonyms associated with alpha Adducin (ADD1)

adducin 1 (ADD1) antibody
adducin 1 (alpha) (Add1) antibody
adducin 1 (Add1) antibody
adducin 1 (alpha) (add1) antibody
adducin 1 (add1) antibody
adducin 1 S homeolog (add1.S) antibody

ADD1 antibody
add1-a antibody
add2 antibody
adda antibody
AI256389 antibody
alpha-adducin antibody
bZ1H20.1 antibody
cb787 antibody
zgc:158352 antibody

Protein level used designations for ADD1

alpha-adducin , erythrocyte adducin alpha subunit , erythrocyte adducin subunit alpha , alpha-ADD , adducin 1 (alpha) , alpha-adducin-like , adducin 2 (beta)

GENE ID	SPECIES
118	Homo sapiens
11518	Mus musculus
24170	Rattus norvegicus
422882	Gallus gallus
507193	Bos taurus
555511	Danio rerio
100172752	Pongo abelii
100401343	Callithrix jacchus
100483493	Ailuropoda melanoleuca
448173	Xenopus (Silurana) tropicalis
394387	Xenopus laevis
488796	Canis lupus familiaris
700805	Macaca mulatta
740376	Pan troglodytes
100015485	Monodelphis domestica
100051451	Equus caballus
100220908	Taeniopygia guttata
100351048	Oryctolagus cuniculus
100541144	Meleagris gallopavo
100564853	Anolis carolinensis
100590491	Nomascus leucogenys
100517353	Sus scrofa
100713878	Cavia porcellus

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Show all anti-Adducin 1 (Alpha) (ADD1) Antibodies with Pubmed References

Human Adducin 1 (Alpha) (ADD1) interaction partners

Mouse (Murine) Adducin 1 (Alpha) (ADD1) interaction partners

Antigen Summary

Alternative names and synonyms associated with alpha Adducin (ADD1)

Protein level used designations for ADD1