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alpha Adducin Products

(Adducin 1 (Alpha) (ADD1))

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Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms\; however, not all variants have been fully described. [provided by RefSeq, Jul 2008].

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Featured alpha Adducin Categories

alpha Adducin Antibodies

High quality antibodies with extensive validation data.

alpha Adducin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended alpha Adducin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7444757
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (10)
Cat. No. ABIN6255485
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, IP, ICC
Validations
  • (5)
Cat. No. ABIN6259794
Quantity 100 μL
Datasheet Datasheet

Recommended alpha Adducin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305967
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418830
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418833
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our alpha Adducin products

Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).

Lin, Nasir, McDonald, Graham, Rommens, Goldberg, Hayden: "Genomic organization of the human alpha-adducin gene and its alternately spliced isoforms." in: Genomics, Vol. 25, Issue 1, pp. 93-9, (1995) (PubMed).

Taylor, Snell, Buckler, Ambrose, Duyao, Church, Lin, Altherr, Bates, Groot: "Cloning of the alpha-adducin gene from the Huntington's disease candidate region of chromosome 4 by exon amplification." in: Nature genetics, Vol. 2, Issue 3, pp. 223-7, (1994) (PubMed).

Joshi, Gilligan, Otto, McLaughlin, Bennett: "Primary structure and domain organization of human alpha and beta adducin." in: The Journal of cell biology, Vol. 115, Issue 3, pp. 665-75, (1991) (PubMed).

Synonyms and alternative names related to alpha Adducin

adducin 1 (ADD1), adducin 1 (alpha) (Add1), adducin 1 (Add1), adducin 1 (alpha) (add1), adducin 1 (add1), adducin 1 S homeolog (add1.S), ADD1, add1-a, add2, ADDA, adda, AI256389, alpha-adducin, bZ1H20.1, cb787, zgc:158352

Protein level used designations for alpha Adducin

  • alpha-adducin
  • erythrocyte adducin alpha subunit
  • erythrocyte adducin subunit alpha
  • alpha-ADD
  • adducin 1 (alpha)
  • alpha-adducin-like
  • adducin 2 (beta)
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