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IL-1 beta Proteins

(Interleukin 1, beta (IL1B))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
IL-1 beta Protein (AA 117-269) (His-Avi Tag) IL-1 beta Protein (AA 117-269) (His-Avi Tag) IL-1 beta Protein (AA 117-269) (His-Avi Tag) (ABIN7274882)

IL1B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC

IL-1 beta Protein (AA 117-269) (His-Avi Tag,Biotin) IL-1 beta Protein (AA 117-269) (His-Avi Tag,Biotin) IL-1 beta Protein (AA 117-269) (His-Avi Tag,Biotin) (ABIN7274883)

IL1B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

IL-1 beta Protein (AA 115-267) (His tag) IL-1 beta Protein (AA 115-267) (His tag) IL-1 beta Protein (AA 115-267) (His tag) (ABIN7123535)

IL1B Origin: Pig Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

IL-1 beta Proteins by Grade

Find IL-1 beta Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

IL-1 beta Proteins by Origin

Find IL-1 beta Proteins for a variety of species such as anti-Human IL-1 beta, anti-Mouse IL-1 beta, anti-Pig IL-1 beta. The species listed below are among those available. Click on a link to go to the corresponding products.

IL-1 beta Proteins by Source

Here you will find IL-1 beta Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

IL-1 beta Proteins by Protein Type

Here you can find IL-1 beta Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

IL-1 beta Proteins by Application

Find IL-1 beta Proteins validated for a specific application such as SDS, WB, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

IL-1 beta Proteins by Biological Activity

Find IL-1 beta Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular IL-1 beta Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (5)
Cat. No. ABIN7274882
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (4)
Cat. No. ABIN7274883
Quantity 100 μg
Datasheet Datasheet
Reactivity Pig
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123535
Quantity 50 μg
Datasheet Datasheet
Reactivity Horse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123532
Quantity 50 μg
Datasheet Datasheet
Reactivity Goat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123530
Quantity 50 μg
Datasheet Datasheet
Reactivity Chicken
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123528
Quantity 50 μg
Datasheet Datasheet
Reactivity Dog
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123529
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964158
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320465
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7321252
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source
Validations
Cat. No. ABIN1111699
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1111690
Quantity 2 μg
Datasheet Datasheet
Reactivity Rabbit
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505461
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1343986
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source CHO Cells
Validations
Cat. No. ABIN2018033
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our IL-1 beta Proteins

Shao, Fang, Dang, Xue, Zhang, Li, Qiao, Cao, Zhuang, Shen, Zhang, Qiao, Li, Gudjonsson, Wang: "Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk." in: Frontiers in immunology, Vol. 10, pp. 746, (2020) (PubMed).

Luo, Huang, He, Liu, Chen, Liu, Mi, Li, Sun, Li, Xiang, Su: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).

Hollborn, Vogler, Reichenbach, Wiedemann, Bringmann, Kohen: "Regulation of the hyperosmotic induction of aquaporin 5 and VEGF in retinal pigment epithelial cells: involvement of NFAT5." in: Molecular vision, Vol. 21, pp. 360-77, (2015) (PubMed).

Ubertini, Norelli, DArcangelo, Gurtner, Cesareo, Baldari, Gentileschi, Piaggio, Nisticò, Soddu, Facchiano, Bossi: "Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist." in: Oncogene, Vol. 34, Issue 19, pp. 2493-504, (2015) (PubMed).

von Burg, Chappaz, Baerenwaldt, Horvath, Bose Dasgupta, Ashok, Pieters, Tacchini-Cottier, Rolink, Acha-Orbea, Finke: "Activated group 3 innate lymphoid cells promote T-cell-mediated immune responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 35, pp. 12835-40, (2014) (PubMed).

Nikolakopoulou, Dutta, Chen, Miller, Trapp: "Activated microglia enhance neurogenesis via trypsinogen secretion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 21, pp. 8714-9, (2013) (PubMed).

Kahlenberg, Thacker, Berthier, Cohen, Kretzler, Kaplan: "Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 6143-56, (2011) (PubMed).

Zhang, Bennett, Verkman: "Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms." in: Annals of neurology, Vol. 70, Issue 6, pp. 943-54, (2011) (PubMed).

Tiwari, Wang, Brochetta, Ke, Vita, Qi, Rivera, Soranzo, Zabucchi, Hong, Blank: "VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways." in: Blood, Vol. 111, Issue 7, pp. 3665-74, (2008) (PubMed).

Yang, Poon, Luo, Cheung, Ho, Lo, Fan: "Up-regulation of vascular endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 4, pp. 2507-15, (2004) (PubMed).

Aliases for IL-1 beta Proteins

interleukin 1 beta (IL1B) Proteins
interleukin 1, beta (IL1B) Proteins
interleukin 1, beta (il1b) Proteins
interleukin 1 beta (Il1b) Proteins
IL-1 Proteins
IL-1 beta Proteins
IL-1B Proteins
Il-1b Proteins
IL-1b Proteins
IL-1BETA Proteins
IL-1beta Proteins
il1-b Proteins
IL1-BETA Proteins
IL1B Proteins
IL1beta Proteins
IL1F2 Proteins
zgc:111873 Proteins
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