Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human Tumor Necrosis Factor Antibodies:
anti-Rat (Rattus) Tumor Necrosis Factor Antibodies:
anti-Mouse (Murine) Tumor Necrosis Factor Antibodies:
Go to our pre-filtered search.
Mouse (Murine) Polyclonal Tumor Necrosis Factor Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900489
Ramkhelawon, Hennessy, Ménager, Ray, Sheedy, Hutchison, Wanschel, Oldebeken, Geoffrion, Spiro, Miller, McPherson, Rayner, Moore: Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. in Nature medicine 2014
Show all 59 Pubmed References
Rat (Rattus) Polyclonal Tumor Necrosis Factor Primary Antibody for WB - ABIN3042522
Zhang, Liu, Goldstein, Li, Ge, He, Fei, Wang, Ruiz: Role of the JAK/STAT signaling pathway in the pathogenesis of acute myocardial infarction in rats and its effect on NF-?B expression. in Molecular medicine reports 2013
Show all 38 Pubmed References
Mouse (Murine) Polyclonal Tumor Necrosis Factor Primary Antibody for WB - ABIN3043313
Liu, Shan, Dong, Liu, Ma, Liu: Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. in World journal of gastroenterology 2013
Show all 38 Pubmed References
Human Polyclonal Tumor Necrosis Factor Primary Antibody for IHC (p), WB - ABIN4886747
Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes. in Natural products and bioprospecting 2015
Show all 38 Pubmed References
Mouse (Murine) Polyclonal Tumor Necrosis Factor Primary Antibody for ELISA, IHC (p) - ABIN3042817
Kan, Zhou, Jin, Yang: Effects of PDTC on NF-?B expression and apoptosis in rats with severe acute pancreatitis-associated lung injury. in International journal of clinical and experimental medicine 2015
Show all 30 Pubmed References
Human Monoclonal Tumor Necrosis Factor Primary Antibody for - ABIN1383955
Hervé, Racadot, Wijdenes, Flesch, Tiberghien, Bordigoni, Holler, Powles, Bourdeau, Wilmer: Monoclonal anti TNF alpha antibody in the treatment of acute GvHD refractory both to corticosteroids and anti IL-2 R antibody. in Bone marrow transplantation 1991
Show all 15 Pubmed References
Human Polyclonal Tumor Necrosis Factor Primary Antibody for ICC, IF - ABIN446837
Kwon, Jung, Hwang, Choi: Evaluation of Bronchiolar and Alveolar Cell Injuries Induced by Short- and Long-term Exposure to Sidestream Smoke. in Korean journal of pathology 2012
Show all 14 Pubmed References
Human Polyclonal Tumor Necrosis Factor Primary Antibody for IF (p), IHC (p) - ABIN677318
Morishita, Oku, Horie, Tonari, Kida, Okubo, Sugiyama, Takai, Hara, Ikeda: Systemic simvastatin rescues retinal ganglion cells from optic nerve injury possibly through suppression of astroglial NF-?B activation. in PLoS ONE 2014
Show all 12 Pubmed References
Human Polyclonal Tumor Necrosis Factor Primary Antibody for IHC (p), IHC - ABIN153474
Roth, Städler, Lemann, Hösli, Simon, Simon: Distinct eosinophil cytokine expression patterns in skin diseases - the possible existence of functionally different eosinophil subpopulations. in Allergy 2011
Show all 11 Pubmed References
Human Polyclonal Tumor Necrosis Factor Primary Antibody for ELISA, ICC - ABIN6269443
Feng, Cui, Gao, Li, Li, Jiang, Tian, Wang, Cui, Cui: Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury. in International journal of molecular medicine 2016
Show all 10 Pubmed References
this is the first evidence to suggest that TET2 (show TET2 Antibodies) mutations promote clonal dominance with aging by conferring TNFalpha resistance to sensitive bone marrow progenitors while also propagating such an inflammatory environment.
Anti-rotavirus effect of TNF-alpha was achieved by NFkappaB (show NFKB1 Antibodies)-regulated genes via the activation of classical nuclear factor kappaB (NF-kappaB (show NFKB1 Antibodies)) signaling.
Results revealed that heterozygous genotype GA of TNF-alpha-238 (rs 361525) SNP significantly increased the risk of adverse-outcome (mortality rate), regardless of organ dysfunction or severity of sepsis.
in the patients with primary depression, depressive symptoms were associated with TNF-alpha
Addition of TNFalpha to podocytes causes CD80 upregulation, actin reorganization and podocyte injury.
The results of the study suggest that the levels of C-reactive protein (show CRP Antibodies) and tumor necrosis factor-alpha are important diagnostic markers of inflammation in patients with chronic pancreatitis and type 2 diabetes mellitus.
TNF-alpha and IL-10 (show IL10 Antibodies) treatment can affect the expression of ICAM-1 (show ICAM1 Antibodies) and CD31 (show HBA1 Antibodies) in human coronary artery endothelial cells.
the results of the present study suggested that overexpression of KLF15 in Eahy926 cells exhibited a protective effect against TNFalpha induced dysfunction via activation of Nrf2 (show GABPA Antibodies) signaling and inhibition of nuclear factor kappaB signaling.
The present study demonstrated the ability of 30 and 100 ng/ml TIMP3 (show TIMP3 Antibodies) to attenuate migration and proliferation, and to inhibit the activity of MMP2 (show MMP2 Antibodies), MMP9 (show MMP9 Antibodies) and TNFalpha secretion of NA SMCs. In conclusion, TIMP3 (show TIMP3 Antibodies) may be considered a potential therapeutic drug for use in a novel drugeluting stent, to attenuate the progressive dilation of the aortic NA.
Elevated A20 (show TNFAIP3 Antibodies) promotes TNF-induced and RIPK1 (show RIPK1 Antibodies)-dependent intestinal epithelial cell death
M. tuberculosis and TNFalpha synergise to induce necroptosis in murine fibroblasts via RIPK1-dependent mechanisms and characterized by phosphorylation of Ser345 of the MLKL necroptosis death effector.
Our current study has demonstrated that in allergic airway disease (AAD) mice, intestinal dysbiosis (ID) caused increased nasal rubbing, sneezing, serum OVA specific IgE level and pro-inflammatory cytokine TNF-alpha in NALF and BALF. ID also inhibited miR (show MLXIP Antibodies)-130a expression in AAD mice. Further molecular experiments indicated that miR (show MLXIP Antibodies)-130a could specifically target and repress TNF-alpha mRNA expression.
These data may indicate that insulin (show INS Antibodies) resistance in Adp(-/-) mice is likely caused by an increase in concentrations of TNFalpha and FFA via downregulation of PPARalpha (show PPARA Antibodies).
TNF-alpha is involved in cardiac PHLPP1 (show PHLPP1 Antibodies) upregulation during reoxygenation, which is mediated by NF-kappaB (show NFKB1 Antibodies) transcriptional activity
TRYP improves the health condition of mice with DSS (show PMP22 Antibodies) induced colitis by regulating the TNF-α/NF-κBp65 and IL-6 (show IL6 Antibodies)/STAT3 (show STAT3 Antibodies) signaling pathways via inhibiting the degradation of IκBα and the phosphorylation of STAT3 (show STAT3 Antibodies).
Lack of TNF-alpha signaling through Tnfr1 (show TNFRSF1A Antibodies) makes the mice more susceptible to acute infection but does not alter state of latency and reactivation of HSV-1.
although TNFalpha does not induce osteoclastogenesis alone, it does work with RANKL to induce osteoclastic differentiation, and the NFkappaB pathway may serve an important role in this process.
two different modes of necroptosis induction by TNFalpha exist which are differentially regulated by iuRIPK1 formation. Overall, this work reveals a distinct mechanism of RIPK1 (show RIPK1 Antibodies) activation that mediates the signaling mechanism of RDA as well as a type of necroptosis.
Data suggest that luteolytic factors (such as TNFa, interferon gamma (show IFNG Antibodies), and PGF2a) control expression of MMP1 (show MMP1 Antibodies), other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.
These results suggest that polymorphism of the TNFalpha-824 A>G gene and mTNFalpha protein expression play an important role in the pathogenesis of enzootic bovine leukosis.
These results suggest that the endometrium might lower the TNF concentration in the blastocyst by (1) regulating TNF secretion into the uterine fluid and (2) inducing decreased TNF and TNFR2 (show TNFRSF1B Antibodies) mRNA transcription in the embryo.
There was a significant association between the proviral load and a low frequency of the G/G genotype of TNF-alpha at position -824.
SNP in the TNF-alpha gene affects immune function and reproductive performance in dairy cows.
Studied genotypic and expression profiling of partial TNF-alpha gene and its association with mastitis susceptibility in 129 crossbred cattle.
Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES (show PTGES Antibodies)), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF) and Fas (show FAS Antibodies) were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.
TNF-alpha up-regulates NaV1.7 (show SCN9A Antibodies) mRNA in both adrenal chromaffin cells and dorsal root ganglia (DRG) neurons, highlighting the peripheral nociceptive mechanism of TNF-alpha
These results provide evidence for a high prevalence of subclinical endometritis in repeat breeding cows as well as the involvement of TNFalpha and iNOS (show NOS2 Antibodies) pathways in the regulation of this pathological condition.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2 (show PTGS2 Antibodies), and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2 (show DAB2 Antibodies), and NR3C1 (show NR3C1 Antibodies). TNF and IL6 (show IL6 Antibodies) levels were also decreased while those of NAMPT (show NAMPT Antibodies) were unaffected.
these findings provide the direct evidence that ADAM17 (show ADAM17 Antibodies) cleaves porcine TNFalpha, which represents a new view for identifying potential therapeutic targets in anti-porcine reproductive and respiratory syndrome virus therapy
TMZ pretreatment effectively reduced the myocardial damage caused by CME via inhibiting the PDCD4 (show PDCD4 Antibodies)/NF-kappaB (show NFKB1 Antibodies)/ TNF-alpha pathway in cardiomyocytes.
TNF-alpha, secreted from activated Monocytes, mediates the downregulation of OTX2 (show OTX2 Antibodies) and essential retinal pigment epithelium genes.
TNF-alpha induced MMP-13 (show MMP13 Antibodies) expression by condylar cells might be involved in the degradation of the juvenile condyle.
TNF-alpha was able to promote theca interna cell proliferation. Our results suggest that TNF-alpha might play a role in hyperandrogenism, cortex thickness, and the increased ovary volume observed in polycystic ovaries.
This study showed that the -791(C-->T) mutation of the TNF-alpha gene could be considered an important potential genetic marker of enterotoxigenic Escherichia coli F18 (show MAMLD1 Antibodies) resistance.
Both Nsp1beta and Nsp11 of porcine reproductive and respiratory syndrome virus were demonstrated to be responsible for the inhibitory effect on TNF-alpha production in pulmonary alveolar macrophages.
Study presents evidence demonstrating a single species of exotoxin ApxI, derived from A. pleuropneumoniae serotype 10, induces the expression and production of proinflammatory cytokines IL-1beta (show IL1B Antibodies), IL-8 (show IL8 Antibodies) and TNF-alpha in porcine alveolar macrophages.
the role of miR (show MYLIP Antibodies)-181a in adipocyte differentiation by regulation of TNF-alpha
The NOS (show NOS Antibodies) inhibitor, L-NMMA, significantly suppressed the combined effects of HT and CORM-2 on TNFalpha-triggered NFkappaBp65 phosphorylation as well as decreased cell viability.
Mecp2 is required for tnfa expression during zebrafish development and inflammation.
Using in vivo, time-lapse imaging we show that as centrally-projecting pioneer axons from dorsal root ganglia (DRG (show COL4A1 Antibodies)) enter the spinal cord, they initiate expression of the cytokine TNFalpha. This induction coincides with ensheathment of these axons by associated glia via a TNF receptor 2 (TNFR2 (show TNFRSF1B Antibodies))-mediated process.
The results reveal a crucial role for TNFalpha/TNFR2 (show TNFRSF1B Antibodies) axis in the protection of the skin against DUOX1 (show DUOX1 Antibodies)-mediated oxidative stress.
proinflammatory cytokines IL-1 (show IL1A Antibodies)/TNFalpha trigger a novel antiviral mechanism involving AID to regulate host cell permissiveness to HBV infection.
TNF alpha is the first molecule identified that is produced by dying retinal neurons and is necessary to induce Muller glia to proliferate in the zebrafish retinal regeneration response.
The data suggest that Mycobacterium marinum SecA2 modulates adaptive immunity to promote granuloma stability, perhaps through induction of tumor necrosis factor alpha.
The data suggest that during infectious pancreatic necrosis virus infection, the expression of cytokines and metalloproteinases might be initiated through the TNFalpha/NF-kappaB (show NFKB1 Antibodies)-mediated pathway.
Infectious pancreatic necrosis virus triggers two death pathways via up-stream induction of the pro-inflammatory cytokine TNFalpha.
Antisense knockdown of tnfa rescued hepatic steatosis and liver degeneration in dtp (show AHCY Antibodies) larvae, whereas the overexpression of tnfa and the hepatic phenotype were unchanged in dtp (show AHCY Antibodies) larvae.
TNF is not required for tuberculous granuloma formation, but maintains granuloma integrity indirectly by restricting mycobacterial growth within macrophages and preventing their necrosis.
These interactions result in the induction of the TNF signaling pathway, activation of apoptosis, and DNA-damage stress response.
Findings showed that both mucosal compartments harbor similar percentages of memory CD4 (show CD4 Antibodies)(+) T cells and displayed comparable cytokine TNF-alpha responses to mitogenic stimulations prior to infection.
Primary role for IL-1beta (show IL1B Antibodies) and TNF-alpha in the triggering of preterm labor associated with inflammation or infection.
The results obtained showed that IL-6 (show IL6 Antibodies) expression in adipose tissue biopsies derived from animals with equine metabolic syndrome was enhanced while TNF-alpha levels of both groups were comparable.
Data indicate that tumor necrosis factor-alpha production is closely related to ovarian steroid actions.
These results indicate that in equine corpus luteum, cytokines TNF, IFNG (show IFNG Antibodies) and FASL (show FASL Antibodies) regulate nitric oxide activity, via eNOS (show NOS3 Antibodies) expression modulation.
These data show the presence of cytokines TNF and IFNG (show IFNG Antibodies), and their receptors, in the equine corpus luteum and indicate their potential involvement in regulation of luteal function.
The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6 (show IL6 Antibodies), IL-10 (show IL10 Antibodies) and TNF-alpha, in horses with recurrent airway obstruction during exacerbation and in remission is reported.
TUNEL staining was positively correlated with TNF-a protein expression. Our findings suggest that apoptosis can be induced in the vocal fold epithelium after 120min of modal intensity phonation. In contrast, shorter durations of vibration exposure do not result in apoptosis signaling.
Inflammatory factors such as TNF-alpha can stimulate MMP-2 (show MMP2 Antibodies)/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases.
The JNK (show MAPK8 Antibodies) pathway plays an important role in mechanical ventilation-stimulated TNF-alpha expression in alveolar macrophages, but the injury-stimulated IL-8 (show IL8 Antibodies) expression may be regulated by other signaling pathways.
The TNFalpha-evoked Cl- current.
IL-1beta (show IL1B Antibodies) and TNF-alpha expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta (show IL1B Antibodies) and TNF-alpha.
Hypercapnia increased expression of TNFa and decreased expression of NFKB in acute lung injury models.
In the early stages of myocardial ischemia, bone marrow stem cells are mobilized and home to ischemic myocardium with a concomitant increase in expression of cytokines VEGF (show VEGFA Antibodies) and TNFalpha.
Ammonium perchlorate can increase gene expressions of types I, III collagens, TGF-beta(1 (show TGFB1 Antibodies)) and TNF-alpha in lung of rabbits.
TNFalpha may either be directly or indirectly involved in vascular damage following an embolic stroke. Moreover, TNFalpha may mediate some of the detrimental effects of tPA (show PLAT Antibodies) on the vascular compartment
Data indicate that three single-nucleotide polymorphisms were identified in tumor necrosis factor-alpha (TNF-alpha) gene.
Macrophage- and neutrophil-derived TNF-alpha instructs skin langerhans cells to prime antiviral immune responses.
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
, TNF, macrophage-derived
, TNF, monocyte-derived
, tumor necrosis factor ligand superfamily member 2
, tumor necrosis factor-alpha
, tumor necrosis factor (TNF superfamily, member 2)
, tumor necrosis factor alpha
, tumor necrosis factor
, tumor-necrosis factor
, tumour necrosis factor
, TNF alpha
, ATP-binding cassette, sub-family F (GCN20), member 1
, tumour necrosis factor alpha
, tumor necrosis factor, alpha
, Tumor necrosis factor ligand superfamily member 2
, TNF-alpha 1