Nlrp4f Protein (AA 1-959) (His tag)
custom-made
NLRP4F
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target
- Nlrp4f (NLRP4F) (NLR Family, Pyrin Domain Containing 4F (NLRP4F))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-959
- Origin
- Mouse
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Nlrp4f protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Nlrp4f Protein expressed in mammalian cells.
- Sequence
- MASFISDFGL IWYLRELNKK EFMKFKDFLI QEILELKLKQ VSSTKVKKAS REDLANLLLK CGENQAWDMT FRILQKINRK DLTERATGAI VGNPNLYRDH LKKKLTHDCP KKFNVRIQDF IKETFIQNDX DAFENLLISK GTERKPHMVF LKGMAGVGKT LMLKNLMLAW SKGLVFQNKF SYAFYFCCQD VKQLKTASLA ELISREWPSP SAPIEEILSQ PEKLLFIIDS LEGMEWDLTK QESELCDDCM EKQPVSTLLS SLLRRKMLPE SSLLLSTTPE TFEKMEDRIQ CTDVKTATAF DERSMKIYFH RLFQDRKRAQ EAFSLVRENK QLFTICQVPL LCWMVATCLK EEIEKGGDPV SLCRRTTSLY TTHIFSLFIP QSAQYPSKKS QDQLQGLCSL AAEGMWTDTF VFGKEALRRN GIFDSDIPTL LDIGMLGKIR EFENSYIFLH PSVQEVCAAI FYMLKRHVEH PSQDVKNIET VLFMFLKKVK TQWIFLGCFI FGLLQKSEQE KLGVFFGHRL SKNIHHKLYQ CLETLSGNAE LQEQIDGMRL FSCLFEMEDE AFLVKAMNCM QQINFVAKNY SDFIVAAYCL KHCSTLKKLS FSTENVLNEG DQSYMEELLI CWNNMCSVFV RSKDIQELRI KDTNFNEPAI RVLYESLKYP SFTLNKLVAN NVSFGDNHVL FELIQNSSLQ YLDLSCSFLS HNEVKLLCDI LNQAECNIEK LMIAHCKLSP DDCKIFGSIL MSSKSLKVLN LASNNLNQGI SSLCKALCHP HCTLEYLVPR SNHCIVNFLL KLSCCGITER GCQDLAEVLK NNQNLKYLHV SYNKLKDTGV MLLCDAIKHP NCHLKDLQLE ACEITDASNE ELCYAFMQCE TLQTLNLMGN AFEVSRMVFF PRKSELMLFI FLHLSRLWIT DFDNEFQAFL LSVKKKNHFL TIRGSVEADG EKKGGDSDAR TMGELSNEI Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- Nlrp4f (NLRP4F) (NLR Family, Pyrin Domain Containing 4F (NLRP4F))
- Alternative Name
- Nlrp4f
- Background
- NACHT, LRR and PYD domains-containing protein 4F (NALP-kappa),FUNCTION: Required for cytoplasmic lattice formation, thereby modulates the distribution of organelles during oocyte maturation and zygote development (PubMed:31575650). Required for preimplantation development in female fertility (PubMed:31575650). May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors (By similarity). {ECO:0000250|UniProtKB:Q96MN2, ECO:0000269|PubMed:31575650}.
- Molecular Weight
- 110.4 kDa
- UniProt
- Q66X05
- AlphaFold
- Q66X05
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