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Niemann-Pick Disease, Type C1 Proteins

(Niemann-Pick Disease, Type C1 (NPC1))

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009].

recommended

NPC1 Protein (AA 151-250) (GST tag) (ABIN1312849)

NPC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

NPC1 Protein (His tag,DYKDDDDK Tag) (ABIN7317151)

NPC1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.

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recommended

NPC1 Protein (His tag) (ABIN7578508)

NPC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, ELISA, SDS

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Niemann-Pick Disease, Type C1 Proteins by Origin

Find Niemann-Pick Disease, Type C1 Proteins for a variety of species such as anti-Human Niemann-Pick Disease, Type C1, anti-Mouse Niemann-Pick Disease, Type C1, anti-Rat Niemann-Pick Disease, Type C1. The species listed below are among those available. Click on a link to go to the corresponding products.

Niemann-Pick Disease, Type C1 Proteins by Source

Here you will find Niemann-Pick Disease, Type C1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Niemann-Pick Disease, Type C1 Proteins by Protein Type

Here you can find Niemann-Pick Disease, Type C1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Niemann-Pick Disease, Type C1 Proteins by Application

Find Niemann-Pick Disease, Type C1 Proteins validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Niemann-Pick Disease, Type C1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

NPC1 Protein (AA 151-250) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1312849

Quantity 10 μg

Datasheet Datasheet

NPC1 Protein (His tag,DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7317151

Quantity 100 μg

Datasheet Datasheet

NPC1 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7578508

Quantity 100 μg

Datasheet Datasheet

NPC1 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7578507

Quantity 100 μg

Datasheet Datasheet

NPC1 Protein (His tag)

Reactivity Human

Source Mammalian Cells

Validations

Cat. No. ABIN7578506

Quantity 100 μg

Datasheet Datasheet

NPC1 Protein

Reactivity Human, Mouse, Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2750647

Quantity 5 applications

Datasheet Datasheet

Aliases for Niemann-Pick Disease, Type C1 Proteins

NPC intracellular cholesterol transporter 1 (NPC1) Proteins
NPC1 like intracellular cholesterol transporter 1 (Npc1l1) Proteins
NPC intracellular cholesterol transporter 1 (Npc1) Proteins
Niemann-Pick disease, type C1 (npc1) Proteins
Niemann-Pick C1 protein (LOC579887) Proteins
9130221N23Rik Proteins
A430089E03Rik Proteins
C85354 Proteins
Cdig2 Proteins
D18Ertd139e Proteins
D18Ertd723e Proteins
Gm243 Proteins
im:7149020 Proteins
lcsd Proteins
nmf164 Proteins
NPC Proteins
spm Proteins
wu:fb53a12 Proteins
wu:fc29a12 Proteins

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Niemann-Pick Disease, Type C1 Proteins by Origin

Niemann-Pick Disease, Type C1 Proteins by Source

Niemann-Pick Disease, Type C1 Proteins by Protein Type

Niemann-Pick Disease, Type C1 Proteins by Application

Popular Niemann-Pick Disease, Type C1 Proteins

Aliases for Niemann-Pick Disease, Type C1 Proteins

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