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Nischarin Proteins

(Nischarin (NISCH))
This gene encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin. In humans, this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes. Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis\; possibly by limiting the expression of alpha-5 integrin. In human cardiac tissue, this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation. Alternative splicing results in multiple transcript variants encoding differerent isoforms. Some isoforms lack the expected C-terminal domains of a functional imidazoline receptor. [provided by RefSeq, Jan 2013].
Nischarin Protein (NISCH) (AA 1-1593) (His tag) Nischarin Protein (NISCH) (AA 1-1593) (His tag) Nischarin Protein (NISCH) (AA 1-1593) (His tag) (ABIN3135991)

Crystallography grade NISCH Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Nischarin Protein (NISCH) (AA 2-1504) (His tag) Nischarin Protein (NISCH) (AA 2-1504) (His tag) Nischarin Protein (NISCH) (AA 2-1504) (His tag) (ABIN3094087)

Crystallography grade NISCH Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Nischarin Protein (NISCH) (AA 1246-1346) (His tag,GST tag) (ABIN7389638)

NISCH Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC

Nischarin Proteins by Grade

Find Nischarin Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Nischarin Proteins by Origin

Find Nischarin Proteins for a variety of species such as anti-Human Nischarin, anti-Mouse Nischarin. The species listed below are among those available. Click on a link to go to the corresponding products.

Nischarin Proteins by Source

Here you will find Nischarin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Nischarin Proteins by Protein Type

Here you can find Nischarin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Nischarin Proteins by Application

Find Nischarin Proteins validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Nischarin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135991
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094087
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7389638
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415323
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312597
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2727329
Quantity 20 μg
Datasheet Datasheet

Aliases for Nischarin Proteins

nischarin (NISCH) Proteins
nischarin (Cyan7822_6841) Proteins
nischarin S homeolog (nisch.S) Proteins
nischarin (nisch) Proteins
nischarin (Nisch) Proteins
1200007D05Rik Proteins
3202002H23Rik Proteins
AW494485 Proteins
hIRAS Proteins
I-1 Proteins
IR1 Proteins
IRAS Proteins
NISCH Proteins
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