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Human Monoclonal ESR2 Primary Antibody for ChIP, DB - ABIN152350
Kuiper, Carlsson, Grandien, Enmark, Haeggblad, Nilsson, Gustafsson: Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. in Endocrinology 1997
Show all 74 Pubmed References
Human Monoclonal ESR2 Primary Antibody for ChIP, ICC - ABIN152348
Bianco, Perry, Smith, Templeton, Montano: Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. in Molecular endocrinology (Baltimore, Md.) 2003
Show all 13 Pubmed References
Human Monoclonal ESR2 Primary Antibody for ChIP, IP - ABIN445498
Burakov, Crofts, Chang, Freedman: Reciprocal recruitment of DRIP/mediator and p160 coactivator complexes in vivo by estrogen receptor. in The Journal of biological chemistry 2002
Show all 9 Pubmed References
Human Monoclonal ESR2 Primary Antibody for IHC, WB - ABIN152349
Fuchsjäger-Mayrl, Nepp, Schneeberger, Sator, Dietrich, Wedrich, Huber, Tschugguel: Identification of estrogen and progesterone receptor mRNA expression in the conjunctiva of premenopausal women. in Investigative ophthalmology & visual science 2002
Show all 5 Pubmed References
Human Monoclonal ESR2 Primary Antibody for IHC (p) - ABIN2473529
Howard: Studies on urinary stone formation: a saga of clinical investigation. in The Johns Hopkins medical journal 1977
Show all 4 Pubmed References
Human Monoclonal ESR2 Primary Antibody for IHC (p) - ABIN2473530
Saunders, Millar, Macpherson, Irvine, Groome, Evans, Sharpe, Scobie: ERbeta1 and the ERbeta2 splice variant (ERbetacx/beta2) are expressed in distinct cell populations in the adult human testis. in The Journal of clinical endocrinology and metabolism 2002
Show all 4 Pubmed References
Cow (Bovine) Polyclonal ESR2 Primary Antibody for GS, ICC - ABIN267203
Muhammad, Maznah, Mahmud, Saeed, Imam, Ishaka: Estrogen receptor modulatory effects of germinated brown rice bioactives in the uterus of rats through the regulation of estrogen-induced genes. in Drug design, development and therapy 2013
Show all 2 Pubmed References
Human Polyclonal ESR2 Primary Antibody for FACS, IF (p) - ABIN725210
Fang, Wu, Huang: Raloxifene upregulated mesangial cell MMP-2 activity via ER-? through transcriptional regulation. in Cell biochemistry and biophysics 2013
Show all 2 Pubmed References
Human Monoclonal ESR2 Primary Antibody for IP, IHC - ABIN2668755
Dan, Cheung, Scriven, Moore: Epitope-dependent localization of estrogen receptor-alpha, but not -beta, in en face arterial endothelium. in American journal of physiology. Heart and circulatory physiology 2003
Show all 2 Pubmed References
Human Polyclonal ESR2 Primary Antibody for WB - ABIN1881321
Fang, Lu, Wang, Wu, Li, Zhang, Pan, Wan: Prognostic impact of ERβ and MMP7 expression on overall survival in colon cancer. in Tumour biology 2010
Show all 2 Pubmed References
Comprehensive genetic analysis for differential functions of esr1, esr2a, and esr2b in fish reproduction.
although esr2b mutant fish showed unaltered antibacterial responses, they were unable to mount an effective antiviral response upon viral challenge.
This study revealed similar patterns of transcript abundance across reproductive morphs for ERbeta1, ERbeta2, ERalpha (show ESR1 Antibodies), and aromatase in the forebrain and saccule.
It was concluded that morpholino (MO) oligonucleotid technology in zebrafish embryos is an good approach for investigating the interplay of estrogen receptor (show ESR1 Antibodies) subtypes in a true physiological context.
during embryogenesis two of the three 17beta-estradiol receptor genes, esr1 and esr2b are expressed, and in presence of ligand the mRNA levels of these two genes increase
Data show that temperature and photoperiod significantly influence the transcription of the estrogen-responsive genes, Vtg1, Vtg2 (show VTG Antibodies), ER alpha (show ESR1 Antibodies) and ER beta after a 21-day exposure to endocrine-disrupting chemicals.
Cloning of the cDNAs corresponding to three oestrogen receptors (esr1 (show ESR1 Antibodies), ERalpha (show ESR1 Antibodies); esr2b, ERbeta1; and esr2a (show ESR1 Antibodies), ERbeta2 ).
Data show that the hepatic expression of estrogen receptor alpha (show ESR1 Antibodies), beta1 and beta2 genes responds differently to estradiol.
genistein binds and activates the three zebrafish estrogen receptors ERalpha (show ESR1 Antibodies), ERbeta-A and ERbeta-B (show ESR1 Antibodies) and induces apoptosis in an ER-independent manner
Estradiol can weakly modulate the motility and this effect is strictly associated with GPER (show GPER Antibodies) and not with ESR1 (show ESR1 Antibodies) and ESR2. The subcellular localization of GPER (show GPER Antibodies) in the neck on stallion sperm is coherent with this effect.
The presence of a single isoform of ESR1 (show ESR1 Antibodies) (66kDa (show SF3A2 Antibodies)) and ESR2 (61kDa) was found by Western-blot analysis in samples from seven stallions and the expression of the seven transmembrane estradiol binding receptor GPER (show GPER Antibodies) in colt testis.
expression of estrogen receptor alpha (show ESR1 Antibodies) and beta and progesterone receptor (show PGR Antibodies) in equine microplacentomes gives evidence for a role of placental steroids as regulators of placental function
cloned three ER subtypes (ERalpha (show ESR1 Antibodies), ERbeta1, and ERbeta2), and examined their developmental expression in the gonads of females and males during embryonic and larval development
The expression of androgen receptors, estrogen receptor beta, and bone morphogenetic protein 2b (show BMP4 Antibodies) in male and female Japanese and Thai medaka are reported.
Data suggest that one alternative splicing variant of Esr2 is "super-activated" by xenoestrogens; here, samples isolated from soil around a landfill site in the United Kingdom appear to contain xenoestrogens that induce cholangitis.
The administration of ICI182,780, which is an agonist of G-protein coupled estrogen receptor (show ESR1 Antibodies) (GPER (show GPER Antibodies)) and an antagonist of ERa and ERb, did not result in protection; however, ICI182,780 significantly blocked EDC-mediated cardioprotection, indicating participation of ERalpha (show ESR1 Antibodies) and/or ERbeta
ERbeta might be the target protein of arctigenin responsible for inhibition of mTORC1 activation and resultant prevention of Th17 cell differentiation and colitis development.
Taken together, the above results clearly demonstrated an mTORC2 (show CRTC2 Antibodies)-dependent regulation of actin polymerization that contributed to the effects of ERalpha (show ESR1 Antibodies) and ERbeta on spatial learning, which may provide a novel target for the prevention and treatment of E2-related dementia in the aged population
Results provide evidence that ERbeta prevents cardiac fibroblasts to undergo fibrosis development.
Increased DNA methylation (show HELLS Antibodies) accompanied this pattern, particularly at CpG dinucleotides located within binding or flanking regions for the transcriptional regulator CCCTC-binding factor (show CTCF Antibodies) of ESR1 (show ESR1 Antibodies) and ESR2, consistent with sustained transcriptional activation of ERa and ERb
These data highlight a new role for ER-beta in adipose biology and its potential to be a safer alternative peripheral therapeutic target for obesity.
Results indicated that puerarin is neuroprotective against Abeta1-42 toxicity via the activation of estrogen receptors, and ERbeta plays a key role in the process. Rindings provide a potential strategy for the prevention of neurodegeneration and the treatment of Alzheimer's disease.
Phosphorylation of myosin regulatory light chain triggered by E2 was found to be mediated by estrogen receptor-beta and the G protein-coupled estrogen receptor (show ESR1 Antibodies).
The present results showed that ER knockout alpha and beta male mice had lower striatal mGlu5 (show GRM5 Antibodies) receptor binding and protein measured by Western blot.
Tumor ERbeta1 expression was available for 911 breast cancer patients and was not associated with ESR2 genotypes. High tumor ERbeta1 expression is a marker of good prognosis in breast cancer, especially among chemotherapy-treated patients, but not in endocrine therapy-treated patients.
the association between four ESR1 (show ESR1 Antibodies) gene variants, and six ESR2 single nucleotide polymorphisms and breast cancer risk in Tunisian women
Targeting ERbeta with selective agonists might affect Hodgkins lymphoma cell proliferation and tumor growth via a mechanism that brings into play DRAM2 (show DRAM2 Antibodies)-dependent autophagic cascade.
Data suggest that the ERalpha (show ESR1 Antibodies)-H19 (show NCKAP1 Antibodies)-BIK (show BIK Antibodies) signaling axis plays an important role in promoting breast cancer cell chemoresistance.
fulvestrant up-regulated ERbeta in ERalpha+/ERbeta (show ESR1 Antibodies)+ breast cancer and in triple negative ERbeta+ breast cancers (ERalpha-/ERbeta (show ESR1 Antibodies)+)
ERbeta plays a crucial role in the cell behavior and extracellular matrix composition of the highly aggressive MDA-MB-231 cells.
Study provides evidence for a critical role of ESR2 in radio-resistance of in head and neck squamous cell carcinoma, and that SMR3A (show SMR3A Antibodies) might serve as a surrogate marker for active ESR2 signaling.
This study demonstrated that ESR2 but not ESR1 (show ESR1 Antibodies) minor alleles were associated with lower cognitive performance in elderly women with an indication of a gene-gene interaction with APOEepsilon4. And also found indications for gene-environment interactions of ESR2 with traffic-related air pollution exposure on cognitive performance.
LY500307 is a highly selective estrogen receptor beta agonist, which loses its selectivity at high dose and leads to undesirable suppression of total testosterone concentration.
There were no statistical differences between the BB genotype and the AB genotype of ESR2 locus in regard to the examined traits. However, a noticeable superiority (P < 0.01) of the BB genotype compared to the homozygous AA genotype, adding almost 2 piglets/litter in TNB and NBA trait, was found.
steroid hormones, AhR (show AHR Antibodies) and estrogen receptor beta are affected by TCDD and genistein in granulosa cells of medium porcine follicles
Results suggest that expression levels of protease activated receptors 1 and 2 (PAR-1 (show F2R Antibodies) and PAR-2 (show F2RL1 Antibodies)) associate with breast cancer outcome in an estrogen receptor (ER (show ESR1 Antibodies))-dependent manner.
results might shed new light on the roles of estrogen receptor (show ESR1 Antibodies) 2(ESR2) in spermatogenesis as candidate for boar fertility
Downregulation of the ERs, particularly ERalpha (show ESR1 Antibodies) in the myometrium and endometrial stroma, might be a relevant mechanism in the antagonism of estrogenic effects by dihydrotestosterone in the pig uterus.
the results of the present study suggest the involvement of estrogen receptor beta in estrogen modulation of pig epididymal function
ERbeta mRNA was found only in Sertoli cells in the testis.
positive staining for ERalpha (show ESR1 Antibodies) in the nuclei of skeletal muscle cells, while the ERbeta stain showed positive signals in nuclei and cytoplasm of skeletal myofibers and myoblasts derived from satellite cells
ESR2 gene polymorphisms are associated with litter size.
The objective of this study was to search for polymorphisms in the coding region of the estrogen receptors 1 and 2 (ESR1 (show ESR1 Antibodies) and ESR2) and to analyze the effects of these variants and the well known intronic ESR1 (show ESR1 Antibodies) PvuII polymorphism on litter size.
The mRNA expression of ER-alpha (show ESR1 Antibodies) and ER-beta in the hypothalamus of developing male and female bovines, is reported.
ER-alpha (show ESR1 Antibodies) is detected predominantly in the soma whereas ER-beta is only present in the nucleus of a few cells in the frontal cortex.
fetal ovary of cattle has the steroidogenic enzyme aromatase (show CYP19A1 Antibodies) to convert androgens to estradiol-17beta, and estrogen receptors alpha and beta to facilitate an estrogen response within the fetal ovary
there are different levels of ERalpha (show ESR1 Antibodies), ERbeta and PR in bovine oviducts at different cycle stages in vivo
The expression of estrogen and progesterone receptors in ovarian follicular structures from cows with cystic ovarian disease (COD (show SNRPB Antibodies)) and a comparison of these with normal ovarian structures are reported.
These data indicate that PGF2alpha, TNFalpha (show TNF Antibodies) and IFNgamma regulate ERalpha (show ESR1 Antibodies) and ERbeta mRNA expressions in bovine luteal cells.
Roles of IGF-I (show IGF1 Antibodies) and the estrogen, androgen and IGF-I (show IGF1 Antibodies) receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells.
The main functional structure domains of the ESR2 in a Jining Gray female goat have been described.
an 17b-estradiol-induced increase in the proliferation of rhesus retinal capillary endothelial cells may be mediated by the action of ERb.
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
, estrogen receptor beta1
, estrogen receptor beta
, estrogen receptor 2 (ER beta)
, estradiol receptor beta
, estrogen receptor beta 2
, estrogen receptor beta 1
, Nuclear receptor subfamily 3 group A member 2
, estrogen receptor beta-like
, ER beta
, nuclear receptor subfamily 3 group A member 2
, oestrogen receptor beta
, estrogen nuclear receptor beta variant a
, estrogen nuclear receptor beta variant b
, estrogen receptor beta 4
, estrogen receptor 2 beta
, steroid receptor
, estrogen receptor 2 (beta)